6317-31-3

Basic information

• Product Name: 3,4-dimethyl-5-phenyl-1,3-oxazolidin-2-one
• CAS NO: 6317-31-3
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.2264
• Mol File: 6317-31-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 370.3°C at 760 mmHg
• Flash Point: 177.8°C
• Density: 1.115g/cm³
• Vapor Pressure: 1.12E-05mmHg at 25°C
• Refractive Index: 1.53
• CAS DataBase Reference: 3,4-dimethyl-5-phenyl-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethyl-5-phenyl-1,3-oxazolidin-2-one(6317-31-3)
• EPA Substance Registry System: 3,4-dimethyl-5-phenyl-1,3-oxazolidin-2-one(6317-31-3)

Safety Data

• Hazardous Substances Data: 6317-31-3(Hazardous Substances Data)

Usage

General Description

3,4-dimethyl-5-phenyl-1,3-oxazolidin-2-one is a chemical compound with the molecular formula C11H13NO2. It is a white crystalline solid and a cyclic organic compound. 3,4-dimethyl-5-phenyl-1,3-oxazolidin-2-one is commonly used as a chiral auxiliary in asymmetric synthesis, particularly in the pharmaceutical industry. Its unique structure allows it to be used in the preparation of various chiral compounds and as a building block for the synthesis of biologically active molecules. It is also used as a catalyst in organic reactions, such as the asymmetric dihydroxylation of alkenes. Additionally, it has potential applications in the development of new pharmaceuticals and agrochemicals due to its ability to influence the stereochemistry of chemical reactions.

Upstream product

• 77-78-1 dimethyl sulfate 
• 7647-01-0 hydrogenchloride 
• 42510-95-2 N-((1RS,2RS)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-urea 
• 54418-69-8 4-methyl-5-phenyl-2-oxazolidinone 
• 74-88-4 methyl iodide 
• 90-81-3 ephedrine 
• 332-25-2 4-(trifluoromethoxy)benzonitrile 
• 299-42-3 2-methylamino-1-phenylpropanol 
• 75-44-5 phosgene 
• 17605-71-9 2-dimethylamino-1-phenyl-propan-1-ol 
• 100-52-7 benzaldehyde 
• 88167-98-0 4-(Diphenyl-phosphinoyl)-3,4-dimethyl-5-phenyl-oxazolidin-2-one 
• 54026-27-6 3-Methyl-4-methyl-5-phenyl-4-oxazolin-2-one 
• 90-82-4 rac-pseudoephedrine 

Downstream Products

• 7632-10-2 methamphetamin 
• 90-82-4 rac-pseudoephedrine 
• 90-81-3 ephedrine 
• 1201-56-5 (+/-)-N-methylephedrine 

Relevant articles and documents

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Synthesis of 2-Arylethylamines by the Curtius Rearrangement

2-Arylethylamine derivatives were synthesized using the Curtius reaction and with three different methods of preparing the acyl azide functional group. Carbamates derived from isocyanate were convenient protecting groups for alkylation of amines. Starting from benzaldehyde, amphetamine was prepared in three steps through an oxazolidin-2-one intermediate in 62% overall yield. Copyright Taylor & Francis Group, LLC.

Oxazolidinone penetration enhancing compounds

Compositions for carrying physiologically active agents through body membranes having the structural formula I: STR1 where: R=H, Alkyl group containing from 1-18 carbon atoms, cycloalkyl, aryl, aralkyl, alkoxy, hydroxyalkyl, alkoyloxyalkyl, acyloxyalkyl and alkoxyalkyl; X=O and NR1, where R1 is selected from H, alkyl, aralkyl acyl group containing from 1-18 carbon atoms, cycloalkyl, hydroxyalkyl, alkoyloxyalkyl acyloxyalkyl and alkoxyalkyl; Y=O and NR2, where R2 is selected from H, alkyl, aralkyl, cycloalkyl, acyl group containing from 1-18 carbon atoms, hydroxyalkyl, alkoyloxyalkyl, acyloxyalkyl and alkoxyalkyl; m=2-4; and n=0-4, are disclosed.