4252-88-4

Usage

InChI:InChI=1/C15H17OP/c1-2-13-17(16,14-9-5-3-6-10-14)15-11-7-4-8-12-15/h3-12H,2,13H2,1H3

Upstream product

• 106-94-5 propyl bromide 
• 603-35-0 triphenylphosphine 
• 111-71-7 heptanal 
• 4141-48-4 allyldiphenylphosphine oxide 
• 55743-31-2 (1-chlorovinyl)diphenylphosphine oxide 
• 927-77-5 n-propylmagnesium bromide 
• 2510-89-6 dipropyl chlorophosphate 
• 71-43-2 benzene 
• 1079-66-9 chloro-diphenylphosphine 
• 4559-70-0 Diphenylphosphine oxide 
• 10173-43-0 propyl dichlorophosphate 
• 4455-77-0 (methoxymethyl)diphenylphosphine oxide 
• 104-88-1 4-chlorobenzaldehyde 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 118032-11-4 (1-Ethyl-1-propenyl)diphenylphosphine oxide 
• 63103-40-2 [2-(Diphenyl-phosphinoyl)-butyl]-trimethyl-silane 
• 78266-85-0 3-diphenylphosphinoyl-9-hydroxynonan-4-one 
• 122552-28-7 3-diphenylphosphinoyl-1-phenylpentan-1-ol 
• 103785-87-1 2-(Diphenyl-phosphinoyl)-1-(4-methoxy-phenyl)-butan-1-ol 
• 89358-54-3 4-diphenylphosphinoyl-2-methoxy-3-methylhexan-3-ol 
• 63103-51-5 2-diphenylphosphinoyl-1-phenylbutan-2-one 
• 64894-07-1 3-Diphenylphosphinoyl-2-methylpentan-2-ol 
• 66164-49-6 1-(Methylthio)-propyl-diphenylphosphinoxid 
• 78266-86-1 (6R,7R)-7-(Diphenyl-phosphinoyl)-nonane-1,6-diol 
• 78266-86-1 (6S,7R)-7-(Diphenyl-phosphinoyl)-nonane-1,6-diol 
• 63103-80-0 (1RS,2RS)-2-Diphenylphosphinoyl-1-phenylbutan-1-ol 
• 63103-80-0 (1RS,2SR)-2-Diphenylphosphinoyl-1-phenylbutan-1-ol 
• 1013636-31-1 n-propyldiphenylphosphine-borane complex 

Relevant academic research and scientific papers

Method for preparation of alkyl phosphonyl compound from peroxide

The invention discloses a method for preparation of an alkyl phosphonyl compound from peroxide. The invention adopts an acyl peroxide as the starting material, and the raw material is easily availableand has a great variety. The product obtained by the method provided by the invention has a great variety and wide uses. Some of the products can be reduced simply into important phosphorus ligands and key pharmaceutical intermediates. In addition, the method avoids the use of high toxicity phosphine reagent, has the characteristics of mild reaction conditions, simple operation, high target product yield, low pollution, simple reaction operation and post-treatment process, and is suitable for industrial production.

Mild and efficient oxidation of phosphorus(III) compounds with Selectfluor

A novel and efficient oxidation of phosphorus(III) compounds with Selectfluor is described. The reactions smoothly led to the formation of tertiary phosphine oxides, phosphinates, and phosphonates in up to 99% yield under mild conditions in minutes.

Iridium(III)-Catalyzed C H Amidation of Arylphosphoryls Leading to a P-Stereogenic Center

Direct C H amidation of arylphosphoryl compounds has been developed by using an IrIIIcatalyst system under mild conditions. A wide range of substrates could be employed with high functional-group tolerance. This procedure was successfully applied for the first time to the asymmetric reaction giving rise to a P-chirogenic center with a high diastereomeric ratio of up to 19:1 (90 % de).

HETEREOCYCLIC AGENT AS CATALYTIC STABILIZING AGENT IN A HYDROFORMYLATION PROCESS

A heterocyclic nitrogen stabilizing agent is employed to reduce the rate of catalyst deactivation in a hydroformylation process.

A novel carbon leaving group in the reaction of organometallic compounds with phosphine oxides

The reaction of diphenyl(methoxymethyl)phosphine oxide 1 with organometallic reagents was found to lead to substitution of the methoxymethyl group. The P-phenyl substituent showed a lower propensity to undergo a displacement.

Reactions of (1-Chlorovinyl)diphenylphosphine Oxide with Organometallic Reagents

Direct substitution of 1-chlorovinyl group by an aryl or an alkyl group in the reactions of (1-chlorovinyl)diphenylphosphine oxide with aryl and alkyl Grignard reagents was observed, whereas in its reactions with the corresponding cuprates addition across the double bond constituted the dominant reaction pathway.

Reactivity of phosphonium diylids with aldehydes and ketones

Non-stabilized and semi-stabilized phosphonium diylids of the type (C6H5)2P(CHR)(CHLiR) (5) show a greater nucleophilic reactivity toward carbonyl compounds than the corresponding monoylids (C6H5)2P(CHR)(CH2R) (8).Thus diylid 5a reacts readily at room temperature with sterically hindered ketones such as fenchone or di-t-butylketone.However, the residual negative charge in the intermediate adduct 13 slows the decomposition to Wittig products and is probably responsible for the observed changes (generally enhancement) in the E-selectivity in the case of non-stabilized as well as semi-stabilized ylids.