4253-24-1

Usage

Uses

Used in Chemical Synthesis:
MELLITIC TRIANHYDRIDE is used as a precursor in the synthesis of various organic compounds and polymers for its ability to form complex structures and contribute to the properties of the final products.
Used in Dye Manufacturing:
MELLITIC TRIANHYDRIDE is used as a key component in the manufacture of dyes, where its chemical structure contributes to the color and stability of the dyes.
Used in Pharmaceutical Production:
MELLITIC TRIANHYDRIDE is used as an intermediate in the production of pharmaceuticals, where it plays a role in the synthesis of active pharmaceutical ingredients.
Used in Agrochemicals:
MELLITIC TRIANHYDRIDE is used in the manufacture of agrochemicals, where it may contribute to the effectiveness of pesticides or other agricultural chemicals.
Used as a Catalyst:
MELLITIC TRIANHYDRIDE is used as a catalyst in certain chemical reactions, where it facilitates the reaction process and improves the yield of the desired products.
Used as a Corrosion Inhibitor:
MELLITIC TRIANHYDRIDE is used as a corrosion inhibitor in metal finishing processes, where it helps to protect metals from corrosion and extends their service life.
It is important to handle MELLITIC TRIANHYDRIDE with care, as prolonged exposure can cause irritation to the skin, eyes, and respiratory system.

Synthetic route

benzenehexacarboxylic acid (517-60-2) → benzene-1,2:3,4:5,6-hexacarboxylic trianhyride (4253-24-1)

Conditions	Yield
With acetyl chloride at 160℃; im Rohr;
With benzoyl chloride
With acetic anhydride
With acetic anhydride for 16h; Heating; Yield given;

benzenehexacarboxylic acid (517-60-2) + acetic anhydride (108-24-7) → benzene-1,2:3,4:5,6-hexacarboxylic trianhyride (4253-24-1)

Conditions	Yield
3-stdg. Erhitzen;

4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE (36768-62-4) + benzene-1,2:3,4:5,6-hexacarboxylic trianhyride (4253-24-1) → C39H54N6O6

Conditions	Yield
With pyridine; acetic anhydride In tetrahydrofuran at 58℃; Solvent; Cooling with ice;	93.3%

benzene-1,2:3,4:5,6-hexacarboxylic trianhyride (4253-24-1) + cobalt(II) chloride (7646-79-9) → cobalt phthalocyanine-1,2:3,4:8,9:10,11:15,16:17,18:22,23:24,15-octakis(dicarboximide) (128096-81-1)

Conditions

Yield

With ammonium molybdate; urea In nitrobenzene mixing hexacarboxylic acid trianhydride, CoCl2, urea, and ammoniummolybdate, adding mixt. to nitrobenzene, heating (2 h, 200°C), adding further urea, heating (2 h); washing (3x, HCl, boiling H2O, MeOH), adding product to concd. H2SO4, shaking (5 h, room temp.), filtering, adding filtrate to ice, standing (several h), centrifuging, decanting, collecting pptn., washing (H2O, EtOH), drying (vac., P2O5); elem. anal.;

83.5%

benzene-1,2:3,4:5,6-hexacarboxylic trianhyride (4253-24-1) + iron(II) chloride → iron phthalocyanine-1,2:3,4:8,9:10,11:15,16:17,18:22,23:24,15-octakis(dicarboximide) (128096-82-2)

Conditions

Yield

With ammonium molybdate; urea In nitrobenzene mixing hexacarboxylic acid trianhydride, FeCl2, urea, and ammoniummolybdate, adding mixt. to nitrobenzene, heating (2 h, 200°C), adding further urea, heating (2 h); washing (3x, HCl, boiling H2O, MeOH), adding product to concd. H2SO4, shaking (5 h, room temp.), filtering, adding filtrate to ice, standing (several h), centrifuging, decanting, collecting pptn., washing (H2O, EtOH), drying (vac., P2O5); elem. anal.;

37.1%

benzene-1,2:3,4:5,6-hexacarboxylic trianhyride (4253-24-1) → tribenzoyl-benzene-1,3,5-tricarboxylic acid

Conditions	Yield
With aluminium trichloride; benzene

benzene-1,2:3,4:5,6-hexacarboxylic trianhyride (4253-24-1) → pentacarbon dioxide (51799-36-1) + Hepta-1,2,3,4,5,6-hexaene-1,7-dione (63615-05-4)

Conditions	Yield
at 900 - 1000℃; Irradiation;

methanol (67-56-1) + benzene-1,2:3,4:5,6-hexacarboxylic trianhyride (4253-24-1) → mellitic acid tetramethyl ester

Conditions	Yield
at 100℃; im Rohr;

benzene-1,2:3,4:5,6-hexacarboxylic trianhyride (4253-24-1) → fullerene-C60 (99685-96-8, 161105-99-3, 161106-00-9, 111138-12-6, 133318-63-5, 134053-11-5, 134931-35-4, 134931-36-5, 139703-76-7, 145633-27-8, 175414-73-0, 175414-74-1, 175414-75-2, 175519-12-7, 175519-13-8, 175519-14-9, 175519-15-0, 136376-46-0, 144906-37-6, 144906-38-7, 151767-00-9, 152882-97-8, 152882-98-9, 152882-99-0, 153062-34-1, 154171-74-1, 154171-75-2, 154333-99-0, 154334-00-6, 154397-63-4, 154460-59-0, 199456-56-9, 108739-25-9, 120329-57-9, 120329-58-0)

Conditions	Yield
In diphenylether org. compd. suspn. refluxing for 24 h under Ar, cooling;
In neat (no solvent) org. compd. heating in evac. quartz tube;

Upstream product

• 517-60-2 benzenehexacarboxylic acid 
• 108-24-7 acetic anhydride 

Relevant academic research and scientific papers

Towards the total synthesis of cyclo[n] carbons and the generation of cyclo[6]carbon

We describe efforts towards the synthesis of some allotropes of carbon, the cyclo[n]carbons where n = 18, 24 and 30. The key intermediate 11 is hexa-1,3,5-triyne with the central triple bond masked as a 1-amino-1,2,3-triazole derivative. Cyclo-oligomerisation of this by oxidative coupling gives macrocyclic precursors of C18, C24 and C30. C30 is a proposed intermediate in the formation of C60 and we also describe some attempts at the synthesis of C60 via the chemical generation of benzotriyne, cyclo[6]carbon.