42538-64-7Relevant academic research and scientific papers
Synthesis and antiplasmodial activity of new heteroaryl derivatives of 7-chloro-4-aminoquinoline
Casagrande, Manolo,Barteselli, Anna,Basilico, Nicoletta,Parapini, Silvia,Taramelli, Donatella,Sparatore, Anna
, p. 5965 - 5979 (2012/10/29)
With the aim to investigate the effect of different heterocyclic rings linked to the 4-aminoquinoline nucleus on the antimalarial activity, a set of 7-chloro-N-(heteroaryl)-methyl-4-aminoquinoline and 7-chloro-N-(heteroaryl)-4- aminoquinoline was synthesi
Aminoacyl Prodrug Derivatives and Medicaments for the Treatment of Thromboembolitic Disorders
-
Page/Page column 16, (2011/02/26)
The present application relates to prodrug derivatives of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of thromboembolic disorders.
AMINOACYL PRODRUGS
-
Page/Page column 20, (2010/12/26)
The present application relates to prodrug derivatives of 5-chloro-N-({(5S)-2-oxo-3-[2-fluoro-4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of thromboembolic disorders.
ACYLOXYMETHYLCARBAMATE PRODRUGS OF OXAZOLIDINONES
-
Page/Page column 49, (2010/02/11)
The present invention relates to acyloxymethylcarbamate oxazolidinones. The compounds of the present invention have potent activity with excellent oral bioavailability against Gram-positive and Gram-negative bacteria.
