425387-58-2

Upstream product

• 97576-82-4 allyl (2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside 
• 405111-56-0 allyl 2-O-acetyl-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->3)-4,6-O-benzylidene-α-D-mannopyranoside 
• 324041-20-5 2-O-acetyl-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1-> 2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate 
• 189324-22-9 (3aS,5R,6R,7S,7aS)-2-Allyloxy-6,7-bis-benzyloxy-5-benzyloxymethyl-2-methyl-tetrahydro-[1,3]dioxolo[4,5-b]pyran 
• 155836-00-3 allyl 4,6-O-benzylidene-α-D-mannopyranoside 
• 425387-57-1 allyl 2-O-acetyl-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->3)-2-O-acetyl-4,6-O-benzylidene-α-D-mannopyranoside 

Relevant academic research and scientific papers

A facile regio- and stereoselective synthesis of mannose octasaccharide of the N-glycan in human CD2 and mannose hexasaccharide antigenic factor 13b

A highly concise and effective synthesis of the mannose octasaccharide of the N-linked glycan in the adhesion domain of human CD2 was achieved via TMSOTf-promoted selective 6-glycosylation of a trisaccharide 4,6-diol acceptor with a pentasaccharide donor, followed by deprotection. The pentasaccharide was constructed by selective 3,6-diglycosylation of 1,2-O-ethylidene-β-D-mannopyranose with 2-O-acetyl-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1 → 2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate, while the trisaccharide was obtained by selective 3-O-glycosylation of allyl 4,6-O-benzylidene-α-D-mannopyranoside with the same disaccharide trichloroacetimidate, followed by debenzylidenation. The mannose hexasaccharide antigenic factor 13b was synthesized by condensation of a trisaccharide donor, 2-O-acetyl-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1 → 2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1 → 3)-4,6-di-O-acetyl-2-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate, with a trisaccharide acceptor, methyl 3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1 → 2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1 → 2)-3,4,6-tri-O-benzoyl-α-D-mannopyranoside, followed by deprotection.