425397-49-5Relevant academic research and scientific papers
Synthesis and biological activity of aminophthalazines and aminopyridazines as novel inhibitors of PGE2 production in cells
Medda, Federico,Sells, Earlphia,Chang, Hui-Hua,Dietrich, Justin,Chappeta, Shashi,Smith, Breland,Gokhale, Vijay,Meuillet, Emmanuelle J.,Hulme, Christopher
, p. 528 - 531 (2013/02/25)
This Letter reports the synthesis and biological evaluation of a collection of aminophthalazines as a novel class of compounds capable of reducing production of PGE2 in HCA-7 human adenocarcinoma cells. A total of 28 analogs were synthesized, a
