42543-45-3

Basic information

• Product Name: Benzoyl azide, 3,4,5-trimethoxy-
• CAS NO: 42543-45-3
• Molecular Formula: C10H11N3O4
• Molecular Weight: 237.215
• Mol File: 42543-45-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoyl azide, 3,4,5-trimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl azide, 3,4,5-trimethoxy-(42543-45-3)
• EPA Substance Registry System: Benzoyl azide, 3,4,5-trimethoxy-(42543-45-3)

Safety Data

• Hazardous Substances Data: 42543-45-3(Hazardous Substances Data)

Upstream product

• 1916-07-0 3,4,5-trimethoxybenzoic acid methyl ester 
• 118-41-2 Eudesmic acid 
• 3291-03-0 3,4,5-trimethoxybenzohydrazide 

Downstream Products

• 109470-61-3 4-(methoxycarbonyl)phenyl 3,4,5-trimethoxybenzoate 
• 109155-52-4 4-(3,4,5-trimethoxy-benzoyloxy)-benzoic acid 
• 39506-08-6 N-carbethoxy-3,4,5-trimethoxy-benzenamine 
• 28506-06-1 N-(1-benzyl-pyrrolidin-3-yl)-3,4,5-trimethoxy-benzamide 
• 1363157-33-8 4,6-decadiyne-1,10-diyl bis[N-(3,4,5-trimethoxyphenyl)carbamate] 
• 1363157-35-0 5,7-decadiyne-1,12-diyl bis[N-(3,4,5-trimethoxyphenyl)carbamate] 
• 1885-35-4 3,4,5-trimethoxybenzonitrile 
• 16807-31-1 γ-(3,4,5-Trimethoxy-phenylmercapto)-acetessigethylester 

Relevant articles and documents

New trimethoxybenzamides and trimethoxyphenylureas derived from dimethylcarbazole as cytotoxic agents. Part i

A convenient synthesis of novel functionalized 1,4-dimethylcarbazole derivatives containing 3,4,5-trimethoxybenzamido-ureido or N-(3,4,5- trimethoxyphenyl)ureido group starting from their corresponding indole derivatives is reported. Three derivatives pre

Synthesis and solid-state polymerization of butadiyne derivatives with Trialkoxyphenylurethane groups

3,4,5-Trialkoxyphenyl isocyanate derivatives, in which alkoxy was dodecyloxy or methoxy, reacted with 4,6- decadiyn-1,10-diol and 5,7-dodecadiyn-1,12-diol, and four butadiyne derivatives with (N-trialkoxyphenyl)urethane groups were successfully synthesized. Their solid-state polymerization stimulated by UV or ￡-ray irradiation was investigated. All monomers in crystals were found to be polymerizable. However, conversion was different depending on the compounds. The derivatives from 5,7-dodecadiyn-1,12-diol showed better conversion, suggesting that they have more favorable monomer arrangement for the solid-state polymerization. Polymers of dodecyloxy derivatives could be partially dissolved in chloroform and they showed solvatochromism when hexane was added to the solution. As was expected from the structure of tridodecyloxyphenyl groups introduced, dodecyloxy derivatives gave organogels in various organic solvents in the concentration less than 2wt%. However, these gels could not be polymerized by UV irradiation, and the monomer alignment was found to be different between crystalline and gel states.

4′-Alkoxyl substitution enhancing the anti-mitotic effect of 5-(3′,4′,5′-substituted)anilino-4-hydroxy-8-nitroquinazolines as a novel class of anti-microtubule agents

Mitosis inhibitors are powerful anticancer drugs. Based on a novel anti-microtubule agent of 5-(4′-methoxy)anilino-4-hydroxy-8-nitroquinazoline, a series of 5-(3′,4′,5′-substituted)anilino-4-hydroxy-8- nitroquinazolines were designed and synthesized to investigate the effect of the substitution on the inhibitory activity against mitotic progression of tumor cells. The large alkoxyl substitution on the 4′-position of 5-anilino ring is beneficial for the potency. The 5-(3′,4′,5′-trimethoxy)anilino-8-nitroquinazoline (1h) displays an overwhelming activity in arresting the cells at the G2/M phase, providing a promising new template for further development of potent microtubule-targeted anti-mitotic drugs.