425431-88-5

Basic information

• Product Name: (3R,αS,1'S,α'R)-tert-butyl 3-(N-benzyloxycarbonyl-N-α-methylbenzylamino)-3-[4-(3'-iso-propoxy-3'-oxo-1'-(N-benzyl-N-α-methylbenzylamino)propyl)phenyl]propanoate
• Synonyms: (3R,αS,1'S,α'R)-tert-butyl 3-(N-benzyloxycarbonyl-N-α-methylbenzylamino)-3-[4-(3'-iso-propoxy-3'-oxo-1'-(N-benzyl-N-α-methylbenzylamino)propyl)phenyl]propanoate
• CAS NO: 425431-88-5
• Molecular Weight: 783.02
• Mol File: 425431-88-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3R,αS,1'S,α'R)-tert-butyl 3-(N-benzyloxycarbonyl-N-α-methylbenzylamino)-3-[4-(3'-iso-propoxy-3'-oxo-1'-(N-benzyl-N-α-methylbenzylamino)propyl)phenyl]propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,αS,1'S,α'R)-tert-butyl 3-(N-benzyloxycarbonyl-N-α-methylbenzylamino)-3-[4-(3'-iso-propoxy-3'-oxo-1'-(N-benzyl-N-α-methylbenzylamino)propyl)phenyl]propanoate(425431-88-5)
• EPA Substance Registry System: (3R,αS,1'S,α'R)-tert-butyl 3-(N-benzyloxycarbonyl-N-α-methylbenzylamino)-3-[4-(3'-iso-propoxy-3'-oxo-1'-(N-benzyl-N-α-methylbenzylamino)propyl)phenyl]propanoate(425431-88-5)

Safety Data

• Hazardous Substances Data: 425431-88-5(Hazardous Substances Data)

Upstream product

• 425431-84-1 (3R,αS,1'S,α'R)-tert-butyl 3-(N-allyl-N-α-methylbenzylamino)-3-[4-(3'-iso-propoxy-3'-oxo-1'-(N-benzyl-N-α-methylbenzylamino)propyl)phenyl]propanoate 
• 425431-86-3 (3S,αR,E)-iso-propyl 3-(N-benzyl-N-α-methylbenzylamino)-3-[4-(3-tert-butoxy-3-oxoprop-1-enyl)phenyl]propanoate 
• 425431-85-2 (3S,αR)-iso-propyl 3-(N-benzyl-N-α-methylbenzylamino)-3-(4-bromophenyl)propanoate 
• 189886-25-7 (E)-iso-propyl 3-(4-bromophenyl)prop-2-enoate 
• 1663-39-4 tert-Butyl acrylate 
• 38235-77-7 (R)-N-benzyl-1-phenylethylamine 
• 3459-92-5 DBC 
• 69032-13-9 dibenzyl iminodicarboxylate 
• 425431-87-4 (3R,αS,1'S,α'R)-tert-butyl 3-(N-α-methylbenzylamino)-3-[4-(3'-iso-propoxy-3'-oxo-1'-(N-benzyl-N-α-methylbenzylamino)propyl)phenyl]propanoate 

Relevant articles and documents

Asymmetric synthesis of homochiral differentially protected bis-β-amino acid scaffolds

A strategy for the asymmetric synthesis of homochiral [(R,R)- or (S,S)-], or meso-(R,S) bis-β-amino acid scaffolds, formally resulting from the stepwise conjugate addition of two differentially protected homochiral lithium amides to two α,β-unsaturated esters attached to a central arene, is demonstrated. Further manipulation enables the efficient synthesis of orthogonally protected pseudo-meso or pseudo-C2 symmetric scaffolds via selective N-benzyl or N-allyl deprotection, enabling regio-, stereo- and chemoselective functionalisation.