425644-15-1

Upstream product

• 1128-56-9 3-amino-1-phenylpyrazole 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 3314-35-0 3-Amino-1-phenyl-2-pyrazoline 

Downstream Products

• 811473-54-8 N-(1-phenylpyrazol-3-yl)-N-(4-piperidyl)propanamide 
• 425644-23-1 N-(1-phenylpyrazol-3-yl)-N-(1-benzyl-4-piperidyl)propanamide 

Relevant academic research and scientific papers

ARYLAMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

The present invention relates to arylamide derivatives having dual pharmacological activity towards both the α2δ subunit, in particular the α2δ-1 subunit,of the voltage-gated calcium channel and the μ-opioid receptor, to processes of preparation of such c

Long-acting fentanyl analogues: synthesis and pharmacology of N-(1-phenylpyrazolyl)-N-(1-phenylalkyl-4-piperidyl)propanamides.

The synthesis of new fentanyl analogues in which the benzene ring of the propioanilido group has been replaced by phenylpyrazole is described. Antinociceptive activity was evaluated using the writhing and hot plate tests in mice. Two compounds, and, showe