426210-64-2

Upstream product

• 26825-95-6 methyl 12-bromododecanoate 
• 94605-71-7 7-benzyl-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane 
• 73367-80-3 12-bromododecanoic acid 

Downstream Products

• 328934-28-7 12-(16-benzyl-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadec-7-yl)-1-{16-[12-(16-benzyl-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadec-7-yl)-dodecanoyl]-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadec-7-yl}-dodecan-1-one 
• 426210-66-4 12-(16-benzyl-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadec-7-yl)-dodecanoic acid 

Relevant academic research and scientific papers

Evidence for multiple alkali metal cation complexation in membrane-spanning ion transporters

The polynitrogen-containing cation transporters 1-4 are shown by electrospray mass spectrometry to form multicationic species. In the absence of Na+, protonated species dominate but increasing the sodium concentration leads to all binding sites

The effect of twin-tailed sidearms on sodium cation transport in synthetic hydraphile cation channels

The preparation of novel tris(macrocycle)s that transport Na+ through phospholipid bilayers is reported. All of the reported structures have the following structural elements: sidechain-macrocycle-spacer-macro-cycle-spacer-macrocycle-sidechain.

Enhancement of cation transport in synthetic hydraphile channels having covalently-linked headgroups

A novel, pentamacrocyclic host molecule has been prepared in which four symmetry-equivalent diazacrown ethers lead to a dramatic enhancement in Na+ transport, across a phospholipid bilayer, relative to open-chained analogs lacking the fourth crown.