426825-75-4

Usage

Uses

Used in Preparational Chemistry:
6-IODOIMIDAZO[1,2-A]PYRIDINE is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure and reactivity make it a valuable component in the preparation of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
6-IODOIMIDAZO[1,2-A]PYRIDINE is used as a building block in the development of new drugs and drug candidates. Its imidazopyridine structure can be further modified and functionalized to create novel compounds with potential therapeutic applications.
Used in Agrochemical Industry:
6-IODOIMIDAZO[1,2-A]PYRIDINE is used as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique chemical properties can contribute to the development of more effective and environmentally friendly products.
Used in Specialty Chemicals Industry:
6-IODOIMIDAZO[1,2-A]PYRIDINE is used as a key intermediate in the production of specialty chemicals, such as dyes, pigments, and other functional materials. Its versatile structure allows for the creation of compounds with specific properties tailored to various applications.

InChI:InChI=1/C7H5IN2/c8-6-1-2-7-9-3-4-10(7)5-6/h1-5H

Upstream product

• 107-20-0 2-chloroethanal 
• 88511-25-5 2-amino-6-iodopyridine 
• 20511-12-0 2-amino-5-iodopyridine 
• 504-29-0 2-aminopyridine 

Downstream Products

• 328062-45-9 6-phenylimidazo[1,2-a]pyridine 
• 958641-89-9 2-[3'-(2-t-butyldiphenylsiloxyethoxy)phenyl]-6-iodoimidazo[1,2-a]pyridine 
• 1205744-34-8 6-(4-fluorophenyl)imidazo[1,2-a]pyridine 
• 955376-51-9 6-methoxyimidazo[1,2-a]pyridine 
• 1205744-38-2 phenyl (6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-yl)carbamate 
• 1205744-37-1 1-(6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-yl)-3-(2-methoxyethyl)urea 
• 1205744-36-0 N-(6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-yl)acetamide 
• 1205744-35-9 N-(6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-yl)cyclopropanecarboxamide 
• 1205744-33-7 3-bromo-6-(4-fluorophenyl)imidazo[1,2-a]pyridine 
• 1205744-32-6 N-(4-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-phenyl)acetamide 
• 1205744-31-5 4-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}aniline 
• 1205744-30-4 6-{[6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]sulphanyl}-1,3-benzothiazol-2-amine 
• 1146615-52-2 3-bromo-6-iodoimidazo[1,2-a]pyridine 
• 690258-23-2 6-iodo-3-nitroimidazo[1,2-a]pyridine 

Relevant academic research and scientific papers

BENZYL-, (PYRIDIN-3-YL)METHYL- OR (PYRIDIN-4-YL)METHYL-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS

The present invention relates to compounds of general formula (I), wherein the groups R1 and R2 are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.

ORGANIC COMPOUNDS

Compounds of formula (I): in free or salt or solvate form, where R1, R2, R3 and R20 have the meanings as indicated in the specification, are useful for treati ng diseases mediated by the ALK-5 and/or ALK-4 receptor. Pharmaceutical composit ions that contain the compounds and processes for preparing the compounds are also described.

NOVEL FUSED IMIDAZOLE DERIVATIVE

The present invention relates to a compound represented by the Formula [I]: Wherein: the A ring is a 5-membered aromatic heterocyclic group containing at least one hetero atom selected from a nitrogen atom, and the like; A1 and A2, are each a nitrogen atom, and the like; X2, X3, X4, and X5 are all carbon atoms, or alternatively any one of X2, X3, X4, and X5 is a nitrogen atom and the rest are all carbon atoms; R1 is a hydrogen atom, or the like; R2, R3, R4, and R5, are each a hydrogen atom, or the like; R6 and R6', are each a hydrogen atom, and the like; R7 is an aryl group and the like; and R8 is an amino group or a hydroxy group, or a pharmaceutically acceptable salt or ester thereof.

PHENYLALANINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

NOVEL COMPOUNDS AS PHARMACEUTICAL AGENTS

The current invention relates to compounds of the formula:(Ia) and the pharmaceutically acceptable salts thereof and their use as TGF-beta signal transduction inhibitors for treating cancer and other diseases in a patient in need thereof by administration of said compounds.

(Hetero)arylation of 6-halogenoimidazo[1,2-a]pyridines differently substituted at C(2): Influence of the 2-substituent on the Suzuki cross-coupling reaction

We previously reported that reactivity towards the Suzuki cross-coupling reaction of 3-iodoimidazo[1,2-a]pyridines substituted at C(2) is largely influenced by the nature of this 2-substituent. Hence, with the aim to expand the scope of this coupling proc