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4-Hydroxy-N-phenylbenzothioamide is a chemical compound with the molecular formula C13H10N2O2S. It is a derivative of benzothioamide, featuring a hydroxyl group at the 4-position and a phenyl group attached to the nitrogen atom. This white crystalline solid is soluble in organic solvents and is used in various chemical reactions and as an intermediate in the synthesis of pharmaceuticals and other organic compounds. Its chemical structure and properties make it a versatile building block in organic chemistry, particularly in the development of new drugs and materials.

4270-58-0

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4270-58-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4270-58-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,7 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4270-58:
(6*4)+(5*2)+(4*7)+(3*0)+(2*5)+(1*8)=80
80 % 10 = 0
So 4270-58-0 is a valid CAS Registry Number.

4270-58-0Relevant academic research and scientific papers

A metal-free and a solvent-free synthesis of thio-amides and amides: An efficient Friedel-Crafts arylation of isothiocyanates and isocyanates

Varun, Begur Vasanthkumar,Sood, Ankush,Prabhu, Kandikere Ramaiah

, p. 60798 - 60807 (2015/02/19)

A rapid, metal-free and solvent-free (very low loading of solvent in few cases) reaction conditions for synthesizing thioamides and amides using a Bronsted super acid such as triflic acid has been developed. This method shows a broad substrate scope with

Sulfated tungstate: An efficient catalyst for synthesis of thioamides via Kindler reaction

Pathare, Sagar P.,Chaudhari, Pramod S.,Akamanchi, Krishnacharya G.

experimental part, p. 125 - 129 (2012/07/03)

New application of sulfated tungstate, a mildly acidic solid inorganic acid, as reusable heterogeneous catalyst for efficient Kindler reaction, a three component reactions of aldehydes, amines and sulfur, for synthesis of thioamides is discussed.

A Simple Method for the Synthesis of Thiobenzamides by Friedel-Crafts Reaction

Jagodzinski, Tadeusz

, p. 717 - 720 (2007/10/02)

The reactions of substituted benzenes and phenols with aliphatic and aromatic isothiocyanates in a nitromethane solution of aluminum chloride give rise to the formation of the secondary thiobenzamides.

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