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2β-deuterioandrost-4-ene-3,17-dione is a synthetic steroid compound that is structurally similar to the naturally occurring hormone testosterone. 2β-deuterioandrost-4-ene-3,17-dione is characterized by the presence of a deuterium atom (a stable isotope of hydrogen) at the 2β position, which differentiates it from its non-deuterated counterpart. The molecule features a four-carbon double bond between carbons 4 and 5, and a ketone group at both the 3 and 17 positions. Due to its structural resemblance to testosterone, 2β-deuterioandrost-4-ene-3,17-dione may exhibit similar biological activities, such as anabolic and androgenic effects. However, the presence of deuterium can potentially alter its metabolic properties and pharmacokinetics, making it a subject of interest in research for potential therapeutic applications or as a tracer in biochemical studies.

4273-40-9

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4273-40-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4273-40-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,7 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4273-40:
(6*4)+(5*2)+(4*7)+(3*3)+(2*4)+(1*0)=79
79 % 10 = 9
So 4273-40-9 is a valid CAS Registry Number.

4273-40-9Relevant academic research and scientific papers

Syntheses of 2α- and 2β-Deuterio-testosterones and -androst-4-ene-3,17-diones

Holland, Herbert L.,Rao, J. Appa,Chenchaiah, P. Chinna

, p. 2027 - 2032 (2007/10/02)

Testosterone and androst-4-ene-3,17-dione with a deuterium label in the 2α- or 2β-position have been synthesized from a common intermediate, 5α-androst-2-ene-5α,17β-diol.An improved preparation of the latter is described, together with its conversion via epoxidation, reductive epoxide opening, and subsequent oxidation and dehydration to 2β-labelled Δ4-3-oxo steroids.Treatment of the same precursor with labelled diborane leads, by a similar synthetic sequence, to both 2α-, and 2β-labelled Δ4-3-oxo steroids.The stereochemical integrity of the products has been determined by high-field deuterium n.m.r.

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