4275-05-2Relevant articles and documents
Flow synthesis of secondary amines over Ag/Al2O3 catalyst by one-pot reductive amination of aldehydes with nitroarenes
Artiukha, Ekaterina A.,Nuzhdin, Alexey L.,Bukhtiyarova, Galina A.,Bukhtiyarov, Valerii I.
, p. 45856 - 45861 (2017/10/06)
An alumina-supported silver catalyst was investigated in the one-pot reductive amination of aldehydes with nitroarenes in a continuous flow reactor using molecular hydrogen as a reducing agent. A series of secondary amines containing alkyl, OH, OCH3, Cl, Br and CC groups was synthesized in good to excellent yields. The yield of the secondary amine depends on the rate of formation of an intermediate imine. It was shown that the accumulation of carbonaceous deposits on the catalyst is the main reason of catalyst deactivation. The spent catalyst can be easily regenerated and reused without losing catalytic activity.
Multisite solid (NHC)NN-Ru-catalysts for cascade reactions: Synthesis of secondary amines from nitro compounds
Del Pozo, Carolina,Corma, Avelino,Iglesias, Marta,Sanchez, Felix
experimental part, p. 110 - 116 (2012/08/08)
Supported ruthenium complexes based on electron-rich (NHC)NN-pincer-type ligands selectively catalyze the formation of substituted amines from nitroaromatics and carbonyl compounds through a series of consecutive steps which involves the reduction of nitro group to amine, the formation of an imine or iminium ion intermediate, followed by in situ reduction to an alkylated amine of higher order in a single operation. Solid complexes result active and recyclable catalysts and no deactivation was observed after repeated recycling.
