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42753-71-9 Usage

Chemical Properties

Light yellow Cryst

Check Digit Verification of cas no

The CAS Registry Mumber 42753-71-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,7,5 and 3 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 42753-71:
119 % 10 = 9
So 42753-71-9 is a valid CAS Registry Number.

42753-71-9 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A12948)  6-Amino-3-bromo-2-methylpyridine, 97%   

  • 42753-71-9

  • 1g

  • 195.0CNY

  • Detail
  • Alfa Aesar

  • (A12948)  6-Amino-3-bromo-2-methylpyridine, 97%   

  • 42753-71-9

  • 5g

  • 762.0CNY

  • Detail
  • Alfa Aesar

  • (A12948)  6-Amino-3-bromo-2-methylpyridine, 97%   

  • 42753-71-9

  • 25g

  • 2357.0CNY

  • Detail
  • Aldrich

  • (548405)  6-Amino-3-bromo-2-methylpyridine  97%

  • 42753-71-9

  • 548405-5G

  • 471.51CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017


1.1 GHS Product identifier

Product name 2-Amino-5-bromo-6-methylpyridine

1.2 Other means of identification

Product number -
Other names 6-Amino-3-bromo-2-picoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:42753-71-9 SDS

42753-71-9Relevant articles and documents

Directing Group Enables Electrochemical Selectively Meta-Bromination of Pyridines under Mild Conditions

Wu, Yanwei,Xu, Shanghui,Wang, Hong,Shao, Dongxu,Qi, Qiqi,Lu, Yi,Ma, Li,Zhou, Jianhua,Hu, Wei,Gao, Wei,Chen, Jianbin

, p. 16144 - 16150 (2021/07/19)

Without the use of catalysts and oxidants, a facile and sustainable electrochemical bromination protocol was developed. By introducing the directing groups, the regioselectivity of pyridine derivatives could be controlled at themeta-position utilizing the inexpensive and safe bromine salts at room temperature. A variety of brominated pyridine derivatives were obtained in 28-95% yields, and the reaction could be readily performed at a gram scale. By combining the installation and removing the directing group, the concept ofmeta-bromination of pyridines could be verified.

multi-links class PI3K inhibitors (by machine translation)


Paragraph 0271; 0272; 0273, (2016/10/09)

The invention belongs to the field of medical technology, in particular of formula (I) shown in multi-links class of PI3K inhibitors, its stereoisomers or its pharmaceutically acceptable salt thereof, wherein the R 1, R 2, R 3, R 4 or R 5 as defined in the specification; the invention also relates to methods of preparing such compounds, pharmaceutical compositions of these compounds in the preparation and treatment and/or prevention of proliferative diseases of the use of the medicament. (by machine translation)

Preparation method of 2-amino-5-methyl-6-bromopyridine


Paragraph 0023; 0024; 0025, (2016/10/07)

For overcoming defects in the prior art, the invention provides a preparation method of 2-amino-5-methyl-6-bromopyridine, which belongs to the technical field of synthesis of pharmaceutical intermediates. The method comprises the following steps: adding an organic solvent subjected to water removal into sodamide under the protection of nitrogen, then heating a solution, and after 2-bromo-3-methylpyridine is added, carrying out reflux reaction on the obtained mixture under the condition that the temperature is kept; and after the reaction is completed, cooling the solution, adding ice water, separating out an upper organic solvent, and sequentially carrying out concentration and crystallization on the organic solvent, so that a product is obtained. According to the invention, a product is directly obtained through one-step amination, therefore, the method is safe and simple in process, and suitable for industrial production.

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