132606-40-7

Basic information

• Product Name: 3-Bromo-6-chloro-2-methylpyridine
• Synonyms: 3-BROMO-6-CHLORO-2-METHYL-PYRIDINE;3-BROMO-6-CHLORO-2-PICOLINE;5-BROMO-2-CHLORO-6-METHYLPYRIDINE;5-BROMO-2-CHLORO-6-PICOLINE;2-Chloro-5-Bromo-6-Picoline
• CAS NO: 132606-40-7
• Molecular Formula: C₆H₅BrClN
• Molecular Weight: 206.47
• Product Categories: blocks;Bromides;Pyridines;Pyridine;Halides;Pyridine series;Variety of halogenated heterocyclic series;Heterocycle-Pyridine series
• Mol File: 132606-40-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: <40℃
• Boiling Point: 80-84℃/2mm lit.
• Flash Point: 87.2 °C
• Appearance: /Liquid
• Density: 1.624 g/cm³
• Vapor Pressure: 0.166mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: soluble in Methanol
• PKA: -1.29±0.10(Predicted)
• CAS DataBase Reference: 3-Bromo-6-chloro-2-methylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-6-chloro-2-methylpyridine(132606-40-7)
• EPA Substance Registry System: 3-Bromo-6-chloro-2-methylpyridine(132606-40-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• RIDADR: UN 2811 6.1 / PGIII
• HazardClass: IRRITANT
• Hazardous Substances Data: 132606-40-7(Hazardous Substances Data)

Usage

General Description

3-Bromo-6-chloro-2-methylpyridine is a chemical compound with the molecular formula C6H5BrClN and a molar mass of 192.47 g/mol. It is a pyridine derivative with bromine, chlorine, and methyl substituents on the pyridine ring. 3-Bromo-6-chloro-2-methylpyridine is mainly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is a white to light yellow solid with a melting point of 68-72°C and a boiling point of 226-227°C. 3-Bromo-6-chloro-2-methylpyridine is also known to be a versatile building block for the preparation of various functionalized pyridine derivatives. It is important to handle this compound with care and appropriate safety measures due to its potential hazards when mishandled.

InChI:InChI=1/C6H5BrClN/c1-4-5(7)2-3-6(8)9-4/h2-3H,1H3

Upstream product

• 164666-68-6 3-amino-6-chloro-2-methylpyridine 
• 22280-60-0 6-chloro-4-methyl-3-nitropyridine 
• 42753-71-9 5-bromo-6-methyl-pyridin-2-ylamine 
• 126717-59-7 3-bromo-6-methoxy-2-methylpyridine 

Downstream Products

• 547756-20-7 3-bromo-2-(bromomethyl)-6-chloropyridine 
• 1374134-49-2 (4S,5R)-3-{[6-azetidin-1-yl-3-bromopyridin-2-yl]methyl}-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one 
• 1374134-53-8 (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[3-bromo-6-(3,3-difluoroazetidin-1-yl)pyridin-2-yl]methyl}-4-methyl-1,3-oxazolidin-2-one 
• 1374135-72-4 (4S,5R)-3-{[6-azetidin-1-yl-3-(2-methoxy-5-nitrophenyl)pyridin-2-yl]methyl}-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one 
• 1374134-56-1 (4S,5R)-3-{[3-(5-amino-2-methoxyphenyl)-6-azetidin-1-ylpyridin-2-yl]methyl}-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one 
• 1374134-55-0 (4S,5R)-3-{[6-azetidin-1-yl-3-(5-iodo-2-methoxyphenyl)pyridin-2-yl]methyl}-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one 
• 1374134-57-2 (4S,5R)-3-({6-azetidin-1-yl-3-[5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-2-methoxyphenyl]pyridin-2-yl}methyl)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one 
• 1374130-71-8 methyl 3-{3-[6-azetidin-1-yl-2-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)pyridin-3-yl]-4-methoxyphenyl}propanoate 
• 1374131-11-9 methyl 5-{3-[6-azetidin-1-yl-2-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)pyridin-3-yl]-4-methoxyphenyl}-4-methylthiophene-2-carboxylate 
• 1374131-12-0 methyl 5-{3-[6-azetidin-1-yl-2-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)pyridin-3-yl]-4-methoxyphenyl}-2-furoate 
• 1374131-28-8 3-{3-[6-azetidin-1-yl-2-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)pyridin-3-yl]-4-methoxyphenyl}propanoic acid 
• 1427324-31-9 8-bromo-5-chloroimidazo[1,5-a]pyridine 
• 439111-18-9 1-(6-chloro-2-methylpyridin-3-yl)ethan-1-one 
• 944316-52-3 methyl 3'-[2-({(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-oxo-1,3-oxazolidin-3-yl}methyl)-6-chloropyridin-3-yl]-4'-methoxy-2-methylbiphenyl-4-carboxylate 

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