42763-75-7Relevant academic research and scientific papers
Synthesis of a new deuterium-labeled phytol as a tool for biosynthetic studies
Munoz, Lourdes,Guerrero, Angel
, p. 862 - 864 (2012)
An efficient and stereoselective synthesis of a new deuterium-labeled phytol as a useful tracer in biosynthetic processes is presented. Georg Thieme Verlag Stuttgart · New York.
AMPHIPHILE PRODRUGS
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Paragraph 0190, (2019/06/12)
Amphiphilic prodrugs of general formula A-X are disclosed, wherein A is a biologically active agent or may be metabolised to a biologically active agent; and X is selected from the group consisting of R, or up to three R moieties attached to a linker, Y1, Y2 or Y3, wherein R is selected from a group consisting of alkyl, alkenyl, alkynyl, branched alkyl, branched alkenyl, branched alkynyl, substituted alkyl, substituted alkenyl and substituted alkynyl groups and their analogues; Y1 is a linker group which covalently attached to an R group at one site and is attached to A at a further independent site; Y2 is a linker group which is covalently attached to two R groups at two independent sites and is attached to A at a further independent site; and Y3 is a linker group which is covalently attached to three R groups at three independent sites and is attached to A at a further independent site. Self-assembly of the amphiphilic prodrugs into reverse lyotropic phases, particularly hexagonal, cubic and sponge, is disclosed. In preferred embodiments A is dopamine or a 5-fluorouracil prodrug.
