42769-38-0Relevant academic research and scientific papers
Synthesis and Some Reactions of 4-Bromo-1,1,3,4-tetrachloro-2-nitro-1,3-butadiene
Potkin, V. I.,Gogolinskii, V. I.,Nechai, N. I.,Zapol'skii, V. A.,Kaberdin, R. V.
, p. 1610 - 1616 (2007/10/03)
4-Bromo-1,1,3,4-tetrachloro-2-nitro-1,3-butadiene was synthesized in 56-68 percent yield by nitration of 4-bromo-1,1,3,4-tetrachloro-1,3-butadiene with a 10:1 HNO3-H3PO4 (or HNO3-H2SO4) mixture.The Z and E isomers of the nitrodiene were separated and characterized by spectral data.The main by-product in the nitration of 4-bromo-1,1,3,4-tetrachloro-1,3-butadiene is 3-bromo-2,3-dichloropropionaldehyde.Its reactions with primary amines result in replacement of the terminal bromine and chlorine atoms and also involve the carbonyl group, yielding corresponding substituted Schiff bases.Reactions of 4-bromo-1,1,3,4-tetrachloro-2-nitro-1,3-butadiene with various primary and secondary amines gave 1,1-diamino-4-bromo-3,4-dichloro-2-nitro-1,3-butadienes; with m-toluidine, the bromine atom is also replaced to give trisubstituted product.
