42781-88-4Relevant academic research and scientific papers
AB-type monomers for the preparation of perfluorocycloalkene (PFCA) aryl ether polymers
Campos, Raymond,Mansur, Aleksander A.,Cook, Chloe H.,Batchelor, Benjamin,Iacono, Scott T.,Smith Jr., Dennis W.
, p. 60 - 68 (2014)
A method for the preparation of AB-type monomers with complimentary fluoro-olefin and phenol functionalities is described. The three-step process is amenable to commercial scale up and uses widely-available, commercial reagents including bisphenols and perfluorocycloalkene (PFCA) compounds. Title compounds and intermediates were characterized via multi-nuclear NMR and FT-IR spectroscopy providing structural and mechanistic elucidation of PFCA step-growth polymerizations. The formation of vinyl and allyl substituted products were quantified and shown to be dependent on PFCA ring size and reaction medium. Nearly equal amounts of vinyl- and allyl-substituted products were observed with perfluorocyclohexene (PFCH) while 2-11% allyl-substitution was observed with perfluorocyclopentene (PFCP), depending on reaction medium polarity. Previous PFCA research and characterization of title compounds suggests that fluoride-catalyzed rearrangement is primarily responsible the formation of two substitution products. Polymerization of an AB-type monomer derived from bisphenol A is demonstrated and was shown to reproducibly result in film-forming polymers with higher molecular weights than previously described methods.
ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE
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Paragraph 0905-0904, (2019/12/15)
Compounds having a structure of formula (I), (I-A), (Ia)-(Ie), (A)-(E), and (II) or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in
AB-type monomers for the preparation of perfluorocycloalkene (PFCA) aryl ether polymers
Campos, Raymond,Mansur, Aleksander A.,Cook, Chloe H.,Batchelor, Benjamin,Iacono, Scott T.,Smith, Dennis W.
, p. 60 - 68 (2014/12/10)
A method for the preparation of AB-type monomers with complimentary fluoro-olefin and phenol functionalities is described. The three-step process is amenable to commercial scale up and uses widely-available, commercial reagents including bisphenols and perfluorocycloalkene (PFCA) compounds. Title compounds and intermediates were characterized via multi-nuclear NMR and FT-IR spectroscopy providing structural and mechanistic elucidation of PFCA step-growth polymerizations. The formation of vinyl and allyl substituted products were quantified and shown to be dependent on PFCA ring size and reaction medium. Nearly equal amounts of vinyl- and allyl-substituted products were observed with perfluorocyclohexene (PFCH) while 2-11% allyl-substitution was observed with perfluorocyclopentene (PFCP), depending on reaction medium polarity. Previous PFCA research and characterization of title compounds suggests that fluoride-catalyzed rearrangement is primarily responsible the formation of two substitution products. Polymerization of an AB-type monomer derived from bisphenol A is demonstrated and was shown to reproducibly result in film-forming polymers with higher molecular weights than previously described methods.
