4279-79-2Relevant academic research and scientific papers
An Ir-photoredox-catalyzed decarboxylative Michael addition of glyoxylic acid acetal as a formyl equivalent
Zhang, Sheng,Tan, Zhoumei,Zhang, Haonan,Liu, Juanli,Xu, Wentao,Xu, Kun
, p. 11642 - 11645 (2017)
We reported herein an iridium-photoredox-catalyzed decarboxylative conjugated addition of glyoxylic acid acetals with various Michael acceptors, including unsaturated amide, ester, aldehyde, ketone, and nitrile under irradiation. Vinyl pyridine and α-aryl styrene are also suitable substrates. The reaction offers various types of acetal products, which are of synthetic significance as protected aldehydes.
