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1,1,2-Trifluoro-1-methoxyethane, also known as methyl trifluoroacetate, is a colorless, volatile liquid with the chemical formula C3H3F3O2. It is an ester derived from trifluoroacetic acid and methanol, featuring a trifluoromethyl group (CF3) and a methoxy group (OCH3) attached to the same carbon atom. 1,1,2-trifluoro-1-methoxyethane is primarily used as a solvent and a reagent in various chemical reactions, particularly in the synthesis of pharmaceuticals and agrochemicals. Due to its unique properties, such as low boiling point, high reactivity, and low toxicity, 1,1,2-trifluoro-1-methoxyethane has gained significant attention in the field of organic chemistry.

428-66-0

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428-66-0 Usage

Physical State

Liquid

Color

Colorless

Odor

Odorless

Flammability

Non-flammable

Applications

Refrigerant in various applications
Solvent for precision cleaning and electronics manufacturing

Environmental Impact

Non-ozone depleting
Low global warming potential
Environmentally friendly

Toxicity

Relatively low toxicity
Not known to cause significant health effects in humans when used as intended

Safety Precautions

Handle with care
Follow safety guidelines to prevent accidental exposure

Check Digit Verification of cas no

The CAS Registry Mumber 428-66-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,2 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 428-66:
(5*4)+(4*2)+(3*8)+(2*6)+(1*6)=70
70 % 10 = 0
So 428-66-0 is a valid CAS Registry Number.

428-66-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,1,2-Trifluoro-1-methoxyethane

1.2 Other means of identification

Product number -
Other names 1,1,2-Trifluorethyl-methylether

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:428-66-0 SDS

428-66-0Downstream Products

428-66-0Relevant academic research and scientific papers

Methyl hypofluorite (MeOF) reactions with various fluoroolefins

Suzuta, Tetsuya,Abe, Takashi,Sekiya, Akira

, p. 3 - 8 (2007/10/03)

The reaction of methyl hypofluorite (MeOF) with certain fluoroolefins, such as CF2=CF2, CF2=CFCF3, CF2=CFOCF3, CF2=CFOMe, CF2=CClF, CF2=CHF, CF2=CH2, CHF=CH2, CF2=CFCF=CF2, occurred in CD3CN or in the presence of NaF. Using neat MeOF in the presence of NaF was a novel method and gave good results. We observed that when more than three fluorine atoms are bonded to the C-C double bond, the addition products were obtained in mostly good yields.

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