4280-89-1

Basic information

• Product Name: 1,4-Pentadien-3-one, 1-(2-furanyl)-5-phenyl-
• CAS NO: 4280-89-1
• Molecular Formula: C15H12O2
• Molecular Weight: 224.259
• Mol File: 4280-89-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,4-Pentadien-3-one, 1-(2-furanyl)-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Pentadien-3-one, 1-(2-furanyl)-5-phenyl-(4280-89-1)
• EPA Substance Registry System: 1,4-Pentadien-3-one, 1-(2-furanyl)-5-phenyl-(4280-89-1)

Safety Data

• Hazardous Substances Data: 4280-89-1(Hazardous Substances Data)

Usage

Physical state

Yellowish liquid

Odor

Strong, sweet

Uses

a. Perfumes and flavorings
b. Chemical intermediate in the synthesis of pharmaceuticals and other organic compounds

Chemical properties

a. Ability to form adducts with a variety of nucleophiles
b. Useful in organic synthesis reactions

Biological properties

a. Anti-inflammatory
b. Antitumor

Potential applications

Drug development

Upstream product

• 98-01-1 furfural 
• 623-15-4 4-(furan-2-yl)but-3-en-2-one 
• 100-52-7 benzaldehyde 
• 122-57-6 1-Phenylbut-1-en-3-one 

Downstream Products

• 92860-50-9 9-Phenyl-nonan-1,7-diol 
• 3208-26-2 9-phenyl-1-hydroxynonane 
• 92581-34-5 1-furan-2-yl-5-phenyl-pentan-3-ol 

Relevant articles and documents

Gram-scale preparation of dialkylideneacetones through Ca(OH)2-catalyzed Claisen-Schmidt condensation in dilute aqueous EtOH

A synthetic method of dialkylideneacetones has been developed. Compared with known protocols, the method employed catalytic Ca(OH)2 as the cheap, mild base catalyst and dilute aqueous EtOH (20%, v/v) as the green and safe solvent. The procedure was easily operated: In most cases, the product could be isolated by a simple filtration, and purified by washing with water. This paper provided experimental details of the reactions, which could be applied in gram-scale synthesis and should be a very reliable and practical protocol to prepare these useful compounds in laboratory and at the industrial level.