42841-31-6Relevant articles and documents
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Johnston,T.P.,Gallagher,A.
, p. 1436 - 1437 (1963)
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Photodisulfidation of alkenes with linear disulfides: Reaction scope and kinetics
Kamps, Joshua T.,Soars, Shafer M.,Bongiardina, Nichloas J.,Fairbanks, Benjamin D.,Bowman, Christopher N.
, (2022/03/07)
Thiol-ene and thiol-yne photomediated conjugations have received substantial attention in research and in practice. Herein is presented the photodisulfidation of alkenes based on the radical-mediated 1:1 reaction of a disulfide and a vinyl ether, which provides an additional route for the formation of the types of sulfides seen in thiol-ene and thiol-yne polymers. Although similar linkages are formed, this approach starting with disulfides is expected to have benefits over the thiol-ene and thiol-yne reactions including extended shelf life of disulfides compared to thiols, reduced shrinkage stress, and increased refractive index of the resulting materials. It was determined that vinyl ethers were the only alkenes capable of undergoing photodisulfidation under ambient conditions and in reasonable timescales. The reaction between vinyl ethers and disulfides performed well in a variety of solvents providing modest to excellent yields (100% for bis(1-methylacetate) disulfide (DSMA)/triethyleneglycol divinylether (TEGDVE)) for numerous disulfide substrates evaluated. It was determined that the mechanism of the photodisulfidation reaction involves an auto-propagating cycle of thiyl radicals which add into either end of a vinyl ether to form thio-ether and thio-acetal linkages in the final product. Finally, although the reaction rate is slower than that of the thiol-ene reaction, the photodisulfidation reaction proceeds relatively rapidly under the explored conditions.
Method for producing high-purity 3-thiohydracrylic acid
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Paragraph 0027; 0028; 0029; 0030, (2016/10/08)
The invention discloses a method for producing high-purity 3-thiohydracrylic acid. The method comprises the following steps that 1, an addition reaction is carried out, wherein acrylonitrile and sodium bisulfide are added to generate 3-mercapto propionic nitrile and sodium sulphide, sodium sulphide can react with acrylonitrile to generate disulfide generation malononitrile, and therefore an addition product is a mixture of 3-mercapto propionic nitrile and disulfide generation malononitrile; 2, a hydrolysis reaction is carried out, wherein in a hydrochloric acid system, the mixture of 3-mercapto propionic nitrile and disulfide generation malononitrile is hydrolyzed into a mixture of 3-thiohydracrylic acid and dithio malonic acid; 3, a reduction reaction is carried out, wherein in the hydrochloric acid system, dithio malonic acid is reduced into 3-thiohydracrylic acid through iron powder, and crude 3-thiohydracrylic acid is obtained after solvent extraction and solvent recovery; 4, a refining procedure is carried out, wherein crude 3-thiohydracrylic acid is rectified to obtain finished 3-thiohydracrylic acid. The defects in the prior art are overcome, the advantages of being low in cost and high in yield are achieved, all the reaction procedures are carried out under normal pressure, three wastes are reutilized, and almost no three wastes are discharged.
