42843-18-5Relevant academic research and scientific papers
Asymmetric dihydroxylation of disubstituted allenes
Fleming, Steven A.,Liu, Renmao,Redd, J. Ty
, p. 8095 - 8098 (2007/10/03)
Asymmetric dihydroxylation of 1,1-disubstituted and 1,3-disubstituted allenes can be used to synthesize chiral α-hydroxy ketones. We have also obtained α,α′-dihydroxy ketones with high enantioselectivity from 1,3-disubstituted allenes. Low conversion of the dihydroxylation of chiral allenes can be used as a kinetic resolution of sterically hindered allenes.
Enantioselective synthesis of α-branched α-hydroxy ketones via chiral N-sulfonyl-2-alkyl-2-cyano-1,3-oxazolidines
Harder, Timm,Loehl, Thorsten,Bolte, Michael,Wagner, Kerstin,Hoppe, Dieter
, p. 7365 - 7368 (2007/10/02)
The stereochemically homogeneous title compounds 6, prepared with two steps from orthoesters and N-tosyl-phenylglycinol 4, afford with two sequential Grignard additions predominantly the tertiary alcohols 8. Electrochemical detosylation, followed by aqueo
A STEREOSELECTIVE SYNTHESIS OF 2-AMINO-2-DEOXY-D-ARABINOSE AND -D-RIBOSE
Mukaiyama, Teruaki,Miwa, Tetsuo,Nakatsuka, Takashi
, p. 145 - 148 (2007/10/02)
Two amino pentoses, 2-acetamido-2-deoxy-D-arabinose and -D-ribose, are conveniently synthesized from 2-amino-2-deoxy-D-pentonic acid derivatives, obtained by the stereoselective reaction of the chiral imine 1 with 2,3-O-isopropylidene-D-glyceraldehyde.
