42843-49-2

Upstream product

• 152212-49-2 1,2-dibromooctane 
• 21948-46-9 1,2-dichlorooctane 
• 109-73-9 N-butylamine 

Downstream Products

• 629-05-0 n-octyne 
• 834899-01-3 1r-Hydroxy-2t--cyclopentan 
• 1461-23-0 tributyltin bromide 
• 122184-69-4 exo-cis-2-(1-octenyl)-3-vinylnorbornane 
• 63922-86-1 2-hexyl-1-phenyl-3-buten-1-ol 
• 75717-41-8 (Z)-oct-1-enylsulfanyl-benzene 
• 75717-40-7 (E)-oct-1-enylsulfanyl-benzene 
• 50284-91-8 ((1Z,3Z)-Octa-1,3-dienyl)-cyclohexane 
• 110897-20-6 ((1Z,3Z)-Deca-1,3-dienyl)-cyclohexane 
• 87028-10-2 (Z)-ethyl dodec-5-enoate 
• 6108-63-0 cis,cis-Hexadeca-7,9-diene 
• 42036-72-6 (Z)-oct-1-enylbenzene 
• 74630-59-4 cis-3-methylundec-4-ene 
• 7206-28-2 (Z)-dodec-5-ene 

Relevant academic research and scientific papers

DIOLS AS EFFECTIVE COCATALYSTS IN THE PHASE TRANSFER CATALYZED PREPARATION OF 1-ALKYNES FROM 1,2-DIHALIDES

Bis-tertiary diols accelerate bis-eliminations of HX from 1,2-dihalides in the presence of an onium salt as phase transfer catalyst and potassium hydroxyde as base.PEG 400 catalyzes the same elimination, but isomerizations from 1-alkyne to mixtures with the 2-alkyne and the 1,2-diene occur easily.

Polyfunctionalized N-Tensides. VII. Substitution and Elimination in the Reaction of 1,2-Dihalogenoalkanes with Amines

1,2-Dichloroalkanes, 1,2-Dibromoalkanes and mixtures of 1-bromo-2-chloroalkanes and 1-chloro-2-bromoalkanes react with primary or secondary amines and give both elimination and substitution products, often in a nearly 1:1 proportion.The elimination products are the cis and trans-1-halo-1-alkenes, the 2-halo-1-alkenes, the 1,3- and 2,4-dienes and the 1-alkenes.The main substitution products are the 1,2-bis-aminoalkanes.Physical dates, 1H-n.m.r.-spectra,surface tension values and CMC-dates are given.

POLY(STYRYLMETHYLTHIOL) AS AN EFFICIENT DEBROMINATING REAGENT OF 1,2-DIBROMIDES

Dibromides are readily debrominated by means of poly(styrylmethyl thiolate) with formation of the respective olefins.The polymeric reagent with a high content of sulphhydryl groups can be easily prepared from chloromethylated polystyrene; it extends possibilities of protection-deprotection reactions of the double bond.

Application of Phase Transfer Catalysis, 14.- Preparation of Alkynes from Halides with Solid Potassium tert-Butoxide and Crown Ether

Preparatively very simple and mild HX eliminations with solid potassium tert-butoxide in petroleum ether in the presence of catalytic amounts of crown-6 are described. 1,2-Dihalides (from alkenes) and 1,1-dihalides (from aldehydes) yield 1-alkynes; internal geminal dihalides (from symmetric ketones) give internal alkynes in excellent yields. 2,2-Dihalides (from methyl ketones) yield homogeneous 1-alkynes only if the 3-position is blocked. (E)-Haloalkenes lead also to alkynes in a syn-elimination process.