42846-15-1Relevant academic research and scientific papers
A novel mitochondria-targeted ratiometric fluorescent probe for endogenous sulfur dioxide derivatives as a cancer-detecting tool
He, Xiao-Ying,Lin, Zhao-Min,Miao, Jun-Ying,Shi, Hao-Nan,Wu, Xiao-Tian,Yang, Di,Zhao, Bao-Xiang
, p. 5722 - 5728 (2020)
A new mitochondria-targeted fluorescent probe RBC, constructed using a coumarin moiety which was selected as the donor and a benzothiazole derivative as the acceptor, for SO2 derivatives (HSO3-/SO32-) was presented. The probe designed on a new FRET platform showed high selectivity and a low detection limit. Importantly, the probe could respond to HSO3-/SO32- within 35 s. Furthermore, the probe could target mitochondria and was successfully used for fluorescence imaging of endogenous bisulfite in HepG2 with low cytotoxicity, which significantly assisted in cancer diagnosis. This journal is
A novel near-infrared fluorescent probe for detecting intracellular alkaline phosphatase and imaging of living cells
Xu, Longbin,He, Xu,Huang, Yibing,Ma, Pinyi,Jiang, Yanxiao,Liu, Xin,Tao, Shuo,Sun, Ying,Song, Daqian,Wang, Xinghua
supporting information, p. 1284 - 1291 (2019/02/28)
Development of novel near-infrared (NIR) fluorescent probes for the monitoring of active substances in living organism is desirable in biological studies. Herein, we designed a novel NIR MTR fluorophore which has a longer emission wavelength, greater Stok
Fluorescent dye, preparation method and applications thereof
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Paragraph 0411; 0414; 0415; 0417; 0461; 0464; 0465; 0468, (2019/10/01)
The invention belongs to the technical field of organic synthesis, and particularly relates to a fluorescent dye, a preparation method and applications thereof, wherein the fluorescent dye has a structural general formula represented by a formula I defined in the specification, X and Y are the same or different O, S, C(CH3)2 or NR6, R2 and R3 are the same or different hydrogen or functional groups, R1, R4, R5 and R6 are all functional groups, and Z is a negative ion. According to the present invention, the fluorescent dye has living cell membrane permeability, can be used for fluorescence imaging of living cell microstructures, and can obtain STED super-resolution fluorescence imaging, laser confocal imaging and other fluorescence imaging of living cells.
Squaric acid dye compounds, preparation method and application
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Paragraph 0066; 0293; 0295; 0296, (2018/06/04)
The invention provides squaric acid dye compounds, a preparation method and an application. The squaric acid dye compounds are shown in formula I, wherein R1, R2, m and n have implications in the description. The squaric acid dye compounds have the characteristics of long absorption wave, high absorption strength, low biotoxicity and the like and can meet the requirement of a photosensitizer.
