428506-75-6

Upstream product

• 106-96-7 propargyl bromide 
• 428506-73-4 S¹-[(1-benzyl-3-chloro-1,6-dihydro-5-methoxy-6-oxo-2-pyrazinyl)methyl]ethanethioate 
• 180893-33-8 1-benzyl-5-chloro-3-methoxy-6-methyl-2(1H)-pyrazinone 
• 173200-35-6 1-benzyl-3,5-dichloro-6-methylpyrazin-2(1H)-one 
• 175468-52-7 1-Benzyl-6-bromomethyl-5-chloro-3-methoxy-1H-pyrazin-2-one 

Downstream Products

• 658071-64-8 1-benzyl-5-chloro-3-methoxy-6-[(2-propynylsulfonyl)methyl]-2(1H)-pyrazinone 
• 180893-33-8 1-benzyl-5-chloro-3-methoxy-6-methyl-2(1H)-pyrazinone 
• 428506-77-8 1-benzyl-3-methoxy-5,7-dihydrothieno[3,4-b]pyridin-2(1H)-one 

Relevant academic research and scientific papers

Generation of 5,6-dimethylene-2(1H)-pyridinones from [3,4-b] sulfolene pyridinones and application in Diels-Alder reactions

2(1H)-Pyrazinones were converted into various [3,4-b] sulfolene pyridinones 19-21, serving as precursors for thermolytic conversion into the corresponding 5,6-dimethylene 2(1H)-pyridinone ortho-quinodimethanes. These were trapped in situ by reaction with

Sulfolene pyridinones as precursors for pyridinone ortho-quinodimethanes and their Diels-Alder adducts

2(1H)-Pyrazinones were converted into [3,4-b] and [3,4-c] sulfolene pyridinones 4 and 5, serving as precursors for the corresponding 3,4- and 5,6-dimethylene 2(1H)-pyridinone ortho-quinodimethanes. These were trapped by in situ reaction with dienophiles. Tethering of 4 also enabled intramolecular cycloaddition.