42860-74-2Relevant academic research and scientific papers
Reductive Desilanolation as a Route to Benzonitriles. An Application to a Concise Synthesis of the Aromatic Sector of Calicheamicin.
Olson, Steven H.,Danishefsky, Samuel J.
, p. 7901 - 7904 (2007/10/02)
The TMS-cyanohydrins of quinones undergo reductive desilanolation in the presence of samarium iodide to form hydroxybenzonitriles.Benzoquinone 1 was converted to the hexasubstituted aromatic fragment of calicheamicin 4 by this method.
