428854-23-3 Usage
Uses
Used in Pharmaceutical Industry:
4,6-PyriMidinediaMine, 2-[1-[(2-fluorophenyl)Methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(phenylazo)is used as a metabolite of stimulators of soluble guanylate cyclase for the treatment of pulmonary hypertension. Its unique molecular structure allows it to potentially modulate the activity of soluble guanylate cyclase, which plays a crucial role in the regulation of vascular tone and blood pressure.
As a result, 4,6-PyriMidinediaMine, 2-[1-[(2-fluorophenyl)Methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(phenylazo)- may offer therapeutic benefits for patients suffering from pulmonary hypertension by improving the efficiency of the guanylate cyclase pathway, leading to vasodilation and reduced blood pressure in the pulmonary circulation. Further research and development are necessary to fully understand the potential applications and optimize the use of 4,6-PyriMidinediaMine, 2-[1-[(2-fluorophenyl)Methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(phenylazo)- in the treatment of pulmonary hypertension and other related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 428854-23-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,8,8,5 and 4 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 428854-23:
(8*4)+(7*2)+(6*8)+(5*8)+(4*5)+(3*4)+(2*2)+(1*3)=173
173 % 10 = 3
So 428854-23-3 is a valid CAS Registry Number.
428854-23-3Relevant academic research and scientific papers
A method for synthesizing [...]
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Paragraph 0029-0031, (2017/03/28)
The invention relates to a method for synthesizing riociguat. The method includes the following steps: 1, a compound 1-(2-fluorobenzyl)-1H-[3,4-b] pyridine derivative-3-formamidine hydrochloride (1) and a compound benzeneazomalononitrile (2) are reacted i
Preparation method and application of pyrazolo[3, 4-b]pyridine compound intermediate
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, (2016/10/17)
The invention provides a preparation method and application of a pyrazolo[3, 4-b]pyridine compound intermediate. Specifically, the intermediate structure is shown as formula IV, wherein the groups are defined as the specification and claims. The intermedi
