42921-40-4 Usage
Uses
Used in Pharmaceutical Industry:
(3β,5β,7α,12α)-3-(ForMyloxy)-7,12-dihydroxycholan-24-oic Acid Methyl Ester is used as an intermediate in the synthesis of 3β-Cholic Acid (C432605), which is a potential metabolite of progesterone (P755900). This makes it a valuable compound in the development of pharmaceuticals targeting hormonal regulation and related health conditions.
Used in Steroid Research:
Due to its structural similarities with bile acids and its potential as a progesterone metabolite, (3β,5β,7α,12α)-3-(ForMyloxy)-7,12-dihydroxycholan-24-oic Acid Methyl Ester can be utilized in research aimed at understanding the role of bile acids and their metabolites in various physiological processes, including cholesterol regulation and hormone balance.
Used in Drug Development:
(3β,5β,7α,12α)-3-(ForMyloxy)-7,12-dihydroxycholan-24-oic Acid Methyl Ester may also be employed in the development of new drugs targeting specific receptors or pathways related to hormonal balance, given its connection to progesterone metabolism. This could lead to the creation of novel therapeutic agents for treating conditions associated with hormonal imbalances or deficiencies.
Check Digit Verification of cas no
The CAS Registry Mumber 42921-40-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,9,2 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 42921-40:
(7*4)+(6*2)+(5*9)+(4*2)+(3*1)+(2*4)+(1*0)=104
104 % 10 = 4
So 42921-40-4 is a valid CAS Registry Number.
42921-40-4Relevant academic research and scientific papers
Denike,Moskova,Zhu
, p. 261 - 267 (1995)
The stereoselective transformation from the commonly occurring 3α-bile acids and derivatives to their 3β-analogs is important for certain applications of these amphiphilic natural compounds, especially in the preparation of polymers. We report here the stereoselective conversion of methyl cholate to its 3β-hydroxy epimer by the use of the Mitsunobu reaction and to a 3β-amino cholic acid analog via a tosylation followed by a S(n)2 displacement with sodium azide and a hydrogenation of the azide group with overall yields of 86% and 78%, respectively. The preparation of the methacrylate and methacrylamide derivatives from these compounds is also described.
