42939-50-4Relevant academic research and scientific papers
Effective gene-silencing of siRNAs that contain functionalized spacer linkages within the central region
Desaulniers, Jean-Paul,Hagen, Gordon,Anderson, Jocelyn,McKim, Chris,Roberts, Blake
, p. 3450 - 3454 (2017/01/24)
Short-interfering RNAs containing a variety of functional groups at the central region of the sense strand were synthesized and evaluated. The gene-silencing data suggest that these siRNAs are biocompatible and are very effective in cell-based assays.
