42956-15-0Relevant academic research and scientific papers
Regioselective addition reaction of organolanthanide reagents to α,β-unsaturated imines
Qian, Changtao,Huang, Taisheng
, p. 143 - 147 (1997)
Organolanthanum reagents[RLaCl2] generated in situ from LaCl3 and alkyl lithium or allyl magnesium could undergo a highly regioselective 1,2-addition to N-alkyl α,β-unsaturated imines, which provided a new and useful approach to synthesize allyl amines with good yields and high regioselectivity. Furthermore, for N-chiral alkyl α,β-unsaturated imine, in the case of n-butyl lithium, the diastereoselectivity achieved highly 90%.
