429687-06-9

Upstream product

• 429687-13-8 di-tert-butyl (4-diethylphosphono-benzyl)malonate 
• 429687-12-7 2-(4-bromo-benzyl)-malonic acid di-tert-butyl ester 
• 429687-04-7 3-(4-diethylphosphono)-propanoic acid 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 77943-39-6 4-methyl-5-phenyloxazolidin-2-one 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 429687-05-8 {4-[3-((4R,5S)-4-Methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-3-oxo-propyl]-phenyl}-phosphonic acid diethyl ester 

Downstream Products

• 429687-08-1 {4-[(S)-2-(Benzyloxycarbonylamino-methyl)-3-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-3-oxo-propyl]-phenyl}-phosphonic acid diethyl ester 
• 429687-09-2 (S)-2-(Benzyloxycarbonylamino-methyl)-3-[4-(diethoxy-phosphoryl)-phenyl]-propionic acid 

Relevant academic research and scientific papers

Enantioselective synthesis of (2S)-2-(4-phosphonophenylmethyl)-3-aminopropanoic acid suitably protected for peptide synthesis

Protected D-β-2-(4-phosphono) phenylalanine was prepared by a multistep synthesis, involving the diastereoselective alkylation of a chiral enolate. This new compound can be further incorporated into peptidic backbone by means of solid-phase peptide synthe