429689-16-7Relevant academic research and scientific papers
Enantioselective friedel-crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes
Evans, David A.,Fandrick, Keith R.,Song, Hyun-Ji,Scheidt, Karl A.,Xu, Risheng
, p. 10029 - 10041 (2008/03/12)
The enantioselective Friedel-Crafts addition of a variety of indoles catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes (Sc(III)-pybox) was accomplished utilizing a series of β-substituted α,β-unsaturated phosphonates and α,β-unsaturate
Enantioselective indole Friedel-Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes
Evans, David A.,Scheidt, Karl A.,Fandrick, Keith R.,Lam, Hon Wai,Wu, Jimmy
, p. 10780 - 10781 (2007/10/03)
A highly enantioselective Friedel-Crafts alkylation of electron-rich aromatic nucleophiles catalyzed by scandium(III) triflate-pyridyl(bis)oxazoline complexes has been accomplished. The reaction involves α,β-unsaturated acyl phosphonates as electrophiles and primarily substituted indoles as nucleophiles. The reactive acyl phosphonate product is converted to the corresponding ester or amide in good overall yield by adding an alcohol or amine directly to the reaction mixture. Copyright
