429690-42-6

Basic information

• Product Name: ethyl 3-bromoH-imidazo[1,2-a]pyridine-5-carboxylate
• Synonyms: ethyl 3-bromoH-imidazo[1,2-a]pyridine-5-carboxylate;Ethyl 3-bromoimidazo[1,2-a]pyridine-5-carboxylate;2-a]pyridine-5-carboxylate;ethyl 3-broMoH-iMidazo[1;IMidazo[1,2-a]pyridine-5-carboxylic acid, 3-broMo-, ethyl ester
• CAS NO: 429690-42-6
• Molecular Formula: C9H9BrN2O3
• Molecular Weight: 273.08336
• Mol File: 429690-42-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.606 g/cm³
• PKA: 1.77±0.50(Predicted)
• CAS DataBase Reference: ethyl 3-bromoH-imidazo[1,2-a]pyridine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-bromoH-imidazo[1,2-a]pyridine-5-carboxylate(429690-42-6)
• EPA Substance Registry System: ethyl 3-bromoH-imidazo[1,2-a]pyridine-5-carboxylate(429690-42-6)

Safety Data

• Hazardous Substances Data: 429690-42-6(Hazardous Substances Data)

Usage

General Description

Ethyl 3-bromoH-imidazo[1,2-a]pyridine-5-carboxylate, also known as ethyl 3-bromo-1H-imidazo[1,2-a]pyridine-5-carboxylate, is a chemical compound with the molecular formula C9H8BrN3O2. It is commonly used in organic synthesis and pharmaceutical research as a key intermediate in the production of various pharmaceuticals and agrochemicals. ethyl 3-bromoH-imidazo[1,2-a]pyridine-5-carboxylate has a pyridine ring and an imidazole ring, making it a versatile building block for the synthesis of various heterocyclic compounds. It is also known for its potential biological activities, particularly as an inhibitor of certain enzymes. Its diverse applications make it a valuable chemical in the field of medicinal and agrochemical chemistry.

Upstream product

• 177485-39-1 ethyl (imidazo[1,2-a]pyridin-5-yl)carboxylate 
• 69142-64-9 ethyl 6-aminopicolinate 

Relevant articles and documents

Efficient synthesis of new polyfunctionalized thiadiazaacenaphthylenes from imidazo[1,2-a]pyridines

New heterocycles containing sulfur and nitrogen with an azaindolizine moiety were synthesized. The imidazo[1,2-a]pyridine-2,5-dicarboxylates (9a, b, 10a, b) and 5-formylimidazo[1,2-a]pyridine-2-carboxylates (17a, b) treated with ethyl thioglycolate and lithium hydroxide underwent ring closure yielding the multifunctional[2,3,3]cyclazines (13) and (18). Under similar conditions, the imidazo[1,2-a]pyridinecarbaldehydes (22a, b) and (29a, b) were converted into the linearly cyclized compounds thieno[3,2-b]imidazo[1,2-a]pyridines (23, 31) and a peri annulated product thiadiazaacenaphthylene (30).