42972-62-3

Basic information

• Product Name: Ethanone, 1-[5-chloro-2-(phenylmethoxy)phenyl]-
• CAS NO: 42972-62-3
• Molecular Formula: C15H13ClO2
• Molecular Weight: 260.72
• Mol File: 42972-62-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[5-chloro-2-(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[5-chloro-2-(phenylmethoxy)phenyl]-(42972-62-3)
• EPA Substance Registry System: Ethanone, 1-[5-chloro-2-(phenylmethoxy)phenyl]-(42972-62-3)

Safety Data

• Hazardous Substances Data: 42972-62-3(Hazardous Substances Data)

Upstream product

• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 584-08-7 potassium carbonate 
• 100-51-6 benzyl alcohol 

Downstream Products

• 87487-56-7 (E)-1-(2-Benzyloxy-5-chloro-phenyl)-3-(3,6-dimethyl-benzofuran-2-yl)-propenone 
• 96755-15-6 1-(2-benzyloxy-5-chlorophenyl)-3-(6-benzodioxan-1,4-yl)propenone 
• 80378-14-9 1-(2-Benzyloxy-5-chlorophenyl)-3-(2-methyl-4-thiazolyl)propenone 
• 114250-22-5 methyl 5-chloro-β-oxo-2-(phenylmethoxy)benzenepropanoate 
• 670275-16-8 1-(2-benzyloxy-5-chloro-phenyl)-ethanol 
• 862814-73-1 1-(2-benzyloxy-5-chloro-phenyl)-butane-1,3-dione 
• 558644-00-1 3-(2-benzyloxy-5-chloro-phenyl)-5-methyl-1H-pyrazole 
• 558644-59-0 3-(2-benzyloxy-5-chloro-phenyl)-4-iodo-5-methyl-1H-pyrazole 
• 558639-14-8 3-(2-benzyloxy-5-chloro-phenyl)-4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-methyl-1H-pyrazole 
• 726180-35-4 1-(2-benzyloxy-5-chlorophenyl)-2-hydroxyethanone 
• 726180-45-6 1-(2-benzyloxy-5-chlorophenyl)-2-methoxymethoxyethanone 
• 726180-56-9 N-[1-(2-benzyloxy-5-chlorophenyl)-2-methoxymethoxyvinyl]acetamide 
• 670275-17-9 4-[1-(2-benzyloxy-5-chloro-phenyl)-ethoxy]-3-ethoxy-benzaldehyde 
• 670275-18-0 {4-[1-(2-benzyloxy-5-chloro-phenyl)-ethoxy]-3-ethoxy-phenyl}-methanol 

Relevant articles and documents

Synthesis of Spirofurooxindoles via Phenyliodine(III) Bis(trifluoroacetate) (PIFA)-Mediated Cascade Oxidative C?O and C?C Bond Formation

Upon treatment with solely a hypervalent iodine reagent of phenyliodine(III) bis(trifluoroacetate) (PIFA), 3-(2-hydroxyphenyl)-3-oxo-N-phenyl propanamides and a series of its derivatives were conveniently converted to a class of undocumented spirofurooxindoles under mild conditions. Control experiments provided evidence that this spirocyclization process encompassed a cascade oxidative reactions involving the formation of a C?O bond prior to that of C?C bond. (Figure presented.).

OXAZOLE AND THIAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PGE2 MEDIATED DISORDERS

Compounds of formula (I) or a pharmaceutiically acceptable derivative thereof: wherein X, Z, Y', Y'', R1 ,R2a, R2b, and Rx are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.

Synthesis of Ether Oligomers

(Equation presented) Hydroxyaromatic aldehydes and ketones were used as building blocks to prepare ether oligomers. An iterative two-step protocol involving Mitsunobu coupling and carbonyl reduction provided a protecting-group-free route with high yields. Activity screening of an 84-member library against proteases led to the discovery of micromolar inhibitors for trypsin, chymotrypsin, and subtilisin.