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ETHYL 3-DI-N-PROPYLAMINOPROPIONATE is a chemical compound characterized by its clear, colorless liquid form with a faint odor. It is soluble in organic solvents but not in water, and is primarily utilized as a precursor in the synthesis of pharmaceutical drugs and other chemical compounds.

42980-55-2

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42980-55-2 Usage

Uses

Used in Pharmaceutical Industry:
ETHYL 3-DI-N-PROPYLAMINOPROPIONATE is used as an intermediate in the synthesis of various pharmaceuticals, particularly for the production of local anesthetics and analgesics. Its role in these applications is crucial for the development of medications that provide pain relief and numbness in targeted areas.
Used in Chemical Industry:
In the chemical industry, ETHYL 3-DI-N-PROPYLAMINOPROPIONATE serves as a building block for the production of other organic compounds. Its versatility in chemical reactions makes it a valuable component in creating a range of different chemical products.
Safety Considerations:
Due to its potential to cause skin and eye irritation, ETHYL 3-DI-N-PROPYLAMINOPROPIONATE should be handled with care. It is recommended to store ETHYL 3-DI-N-PROPYLAMINOPROPIONATE in a cool, dry place, away from sources of heat and ignition to prevent any hazardous incidents.

Check Digit Verification of cas no

The CAS Registry Mumber 42980-55-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,9,8 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 42980-55:
(7*4)+(6*2)+(5*9)+(4*8)+(3*0)+(2*5)+(1*5)=132
132 % 10 = 2
So 42980-55-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H23NO2/c1-4-8-12(9-5-2)10-7-11(13)14-6-3/h4-10H2,1-3H3

42980-55-2Relevant academic research and scientific papers

Design and evaluation of switchable-hydrophilicity solvents

Vanderveen, Jesse R.,Durelle, Jeremy,Jessop, Philip G.

, p. 1187 - 1197 (2014/03/21)

Switchable-hydrophilicity solvents (SHSs) are solvents that can switch reversibly between one form that is miscible with water to another that forms a biphasic mixture with water. For these SHSs, we use CO2 at 1 bar as a stimulus for triggering the transformation to the water-miscible form and removal of CO2 to achieve the reverse. We now report the identification of 13 new SHSs, including the first secondary amine SHSs, and a comparison of all known SHSs in terms of safety and environmental impacts. Amines which include another functional group, especially oxygen-containing groups, are less hazardous than alkylamines. Secondary amines can have improved switching speeds relative to tertiary amines. The variety of SHSs identified suggests that amine SHSs can be designed to have ideal properties for a given application.

Titania nanoparticles stabilized HPA in SBA-15 for the intermolecular hydroamination of activated olefins

Sawant-Dhuri, Dhanashri,Balasubramanian, Veerappan V.,Ariga, Katsuhiko,Park, Dae-Hwan,Choy, Jin-Ho,Cha, Wang Soo,Al-Deyab, Salem S.,Halligudi, Shivappa B.,Vinu, Ajayan

, p. 3347 - 3354 (2015/04/16)

A liquid phase hydroamination (HA) of α,β-ethylenic compounds with amines was investigated with TiO2 nanoparticles stabilized 12-tungstophosphoric acid (TPA) in SBA-15. The catalysts were prepared by wet impregnation of TPA/TiO2 nanoparticles into the SBA-15 and calcined at different temperatures. The characterization results reveal that the textural properties and the acidity of the prepared catalysts can be finely controlled with the simple adjustment of the calcination temperature and the structure of the support, decorated with the TiO2 and TPA nanoparticles, was intact even after the modification. The prepared catalysts were investigated for HA of ethyl acrylate with different aromatic and aliphatic amines over a wide range of reaction conditions to optimize the yield and the selectivity of product. It was found that this process is 100% atom efficient and the catalytic performance depended significantly on the loading of TPA over the catalyst and the calcination temperature. Under optimized reaction conditions, the best catalyst, 15 wt%TPA/22.4 wt%TiO2/SBA-15 calcined at 1123 K, offered the highest conversion of p-ethylaniline (70%) with 100% chemo-selectivity to the anti-Markovnikov product, i.e., the mono-addition product. The reaction was heterogeneously catalyzed and no contribution from leached TPA into the reaction was observed.

A green, ionic liquid and quaternary ammonium salt-catalyzed aza-Michael reaction of α,β-ethylenic compounds with amines in water

Xu, Li-Wen,Li, Jing-Wei,Zhou, Shao-Lin,Xia, Chun-Gu

, p. 183 - 184 (2007/10/03)

The first environmentally benign, highly efficient conjugate addition of aliphatic amines to α,β-unsaturated compounds catalysed by simple quaternary ammonium salts and ionic liquids in the green solvent, water, is described.

Efficient Copper-Catalyzed Chemo Selective Conjugate Addition of Aliphatic Amines to α,β-Unsaturated Compounds in Water

Xu, Li-Wen,Li, Jing-Wei,Xia, Chun-Gu,Zhou, Shao-Lin,Hu, Xiao-Xue

, p. 2425 - 2427 (2007/10/03)

The first environmentally benign, highly efficient, conjugate addition of aliphatic amines to α,β-unsaturated compounds catalyzed by simple copper salts in the green solvent, water is described.

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