42980-55-2

Basic information

• Product Name: ETHYL 3-DI-N-PROPYLAMINOPROPIONATE
• Synonyms: ETHYL 3-DI-N-PROPYLAMINOPROPIONATE;ETHYL-BETA-DIPROPYLAMINOPROPIONATE;ethyl N,N-dipropyl-beta-alaninate;ETHYL 3-(DIPROPYLAMINO)PROPIONATE;ethyl 3-(dipropylamino)propanoate
• CAS NO: 42980-55-2
• Molecular Formula: C₁₁H₂₃NO₂
• Molecular Weight: 201.31
• EINECS: 256-034-3
• Mol File: 42980-55-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 254.7°Cat760mmHg
• Flash Point: 81.4°C
• Appearance: /
• Density: 0.911g/cm³
• Vapor Pressure: 0.017mmHg at 25°C
• Refractive Index: 1.442
• CAS DataBase Reference: ETHYL 3-DI-N-PROPYLAMINOPROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-DI-N-PROPYLAMINOPROPIONATE(42980-55-2)
• EPA Substance Registry System: ETHYL 3-DI-N-PROPYLAMINOPROPIONATE(42980-55-2)

Safety Data

• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot
• Hazardous Substances Data: 42980-55-2(Hazardous Substances Data)

Usage

General Description

Ethyl 3-di-n-propylaminopropionate is a chemical compound primarily used in the production of pharmaceutical drugs and as a precursor to other chemical compounds. It is a clear, colorless liquid with a faint odor, and it is soluble in organic solvents but insoluble in water. ETHYL 3-DI-N-PROPYLAMINOPROPIONATE is mainly used as an intermediate in the synthesis of various pharmaceuticals such as local anesthetics and analgesics. It is also used in the chemical industry as a building block for the production of other organic compounds. Safety data on this compound indicates that it should be handled with care due to its potential to cause skin and eye irritation, and it should be stored in a cool, dry place away from sources of heat and ignition.

InChI:InChI=1/C11H23NO2/c1-4-8-12(9-5-2)10-7-11(13)14-6-3/h4-10H2,1-3H3

Upstream product

• 20732-22-3 3-(dipropylamino)propanenitrile 
• 64-17-5 ethanol 
• 623-71-2 ethyl 3-chloropropanoate 
• 142-84-7 di-n-propylamine 
• 54221-37-3 diethyl meso-2,5-dibromoadipate 
• 140-88-5 ethyl acrylate 

Downstream Products

• 768295-68-7 3-dipropylamino-1,1-diphenyl-propan-1-ol 
• 90795-57-6 β-Dipropylaminopropionhydrazid 

Relevant articles and documents

Design and evaluation of switchable-hydrophilicity solvents

Switchable-hydrophilicity solvents (SHSs) are solvents that can switch reversibly between one form that is miscible with water to another that forms a biphasic mixture with water. For these SHSs, we use CO2 at 1 bar as a stimulus for triggering the transformation to the water-miscible form and removal of CO2 to achieve the reverse. We now report the identification of 13 new SHSs, including the first secondary amine SHSs, and a comparison of all known SHSs in terms of safety and environmental impacts. Amines which include another functional group, especially oxygen-containing groups, are less hazardous than alkylamines. Secondary amines can have improved switching speeds relative to tertiary amines. The variety of SHSs identified suggests that amine SHSs can be designed to have ideal properties for a given application.

A green, ionic liquid and quaternary ammonium salt-catalyzed aza-Michael reaction of α,β-ethylenic compounds with amines in water

The first environmentally benign, highly efficient conjugate addition of aliphatic amines to α,β-unsaturated compounds catalysed by simple quaternary ammonium salts and ionic liquids in the green solvent, water, is described.

SYNTHESIS OF ALIPHATIC AMINO-ACID HYDRAZIDES AS POTENTIAL

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