43010-46-4Relevant academic research and scientific papers
Hypoxia-inducible factor-1 and nuclear factor-κB inhibitory meroterpene analogues of bakuchiol, a constituent of the seeds of Psoralea corylifolia
Wu, Cheng-Zhu,Hong, Seong Su,Cai, Xing Fu,Dat, Nguyen Tien,Nan, Ji-Xing,Hwang, Bang Yeon,Lee, Jung Joon,Lee, Dongho
, p. 2619 - 2623 (2008)
Two new meroterpenoids, 12,13-dihydro-12,13-dihydroxybakuchiol (2) and (12′S)-bisbakuchiol C (3), were isolated from the seeds of Psoralea corylifolia L. (Fabaceae). The structures of 2 and 3 were elucidated by spectroscopic and chemical methods. Six mero
Synthesis and evaluation of bakuchiol derivatives as potential anticancer agents
Wu, Cheng-Zhu,Liu, Da-Chuan,Guo, Xing,Dai, Yiqun,Ma, Tao,Li, Hong-Mei,Huo, Qiang
, (2018/03/09)
A series of bakuchiol derivatives were synthesized and evaluated for their anti-proliferative and the inhibitory activities on SMMC7721 cell line migration using PX-478 as a positive control. The results showed (S,E)-4-(7-methoxy-3,7-dimethyl-3-vinyloct-1
Bakuchiol derivatives as novel and potent cytotoxic agents: A report
Majeed, Rabiya,Reddy, Mallepally V.,Chinthakindi, Praveen K.,Sangwan, Payare L.,Hamid, Abid,Chashoo, Gousia,Saxena, Ajit K.,Koul, Surrinder
experimental part, p. 55 - 67 (2012/04/10)
A library of 28 compounds comprising of acyl, amino, halo, nitro, styryl and cyclized derivatives of bakuchiol have been evaluated against a panel of eight human cancer cell lines. Bioevaluation studies have resulted in the identification of potent cytoto
Novel bisstyryl derivatives of bakuchiol: Targeting oral cavity pathogens
Mallepally V. Reddy,Niranjan Thota,Payare L. Sangwan,Pankaj Malhotra,Furqan Ali,Inshad A. Khan,Swapandeep S. Chimni,Koul, Surrinder
experimental part, p. 3125 - 3134 (2010/09/03)
Novel bisstyryl derivatives of bakuchiol using Heck coupling reaction as the key step were synthesized and screened against a panel of six oral cavity pathogens for their antimicrobial activity. Four compounds (9-12) showed two to fourfold and four to eig
