43017-75-0

Basic information

• Product Name: Naphthalen-1-yl-acetaldehyde
• Synonyms: Naphthalen-1-yl-acetaldehyde;2-(naphthalen-1-yl)acetaldehyde
• CAS NO: 43017-75-0
• Molecular Formula: C₁₂H₁₀O
• Molecular Weight: 170.2072
• Mol File: 43017-75-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 33.5 °C
• Boiling Point: 163-166 °C(Press: 13 Torr)
• Appearance: /
• Density: 1.107±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Naphthalen-1-yl-acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalen-1-yl-acetaldehyde(43017-75-0)
• EPA Substance Registry System: Naphthalen-1-yl-acetaldehyde(43017-75-0)

Safety Data

• Hazardous Substances Data: 43017-75-0(Hazardous Substances Data)

Usage

General Description

Naphthalen-1-yl-acetaldehyde is a chemical compound with the molecular formula C12H10O. It is an aldehyde derivative of naphthalene, an aromatic hydrocarbon commonly found in coal tar and used in the production of dyes, moth repellents, and solvents. Naphthalen-1-yl-acetaldehyde is primarily used in the synthesis of pharmaceuticals and agrochemicals due to its potential for biological activity. It has been studied for its antibacterial, antifungal, and anti-inflammatory properties, as well as its potential as a treatment for neurodegenerative diseases. However, it is important to handle this chemical with caution, as it can be toxic if ingested or inhaled and can cause irritation to the skin and eyes.

Upstream product

• 86-87-3 naphth-1-yl acetic acid 
• 826-74-4 1-vinylnaphthalene 

Downstream Products

• 86-87-3 naphth-1-yl acetic acid 
• 2091-90-9 1,2,3,4-tetrahydrochryzene 
• 874338-50-8 1-(1-naphthyl)-4-phenylbut-3-yn-2-ol 
• 2840-88-2 (Z)-1-styrylnaphthalene 
• 2840-87-1 (E)-1-styrylnaphthalene 
• 1145661-07-9 C₂₆H₃₀N₄O₃ 
• 1260254-05-4 (R,R)-N,N'-dimethyl-N,N'-bis(2-(naphthalen-1-yl)ethyl)-1,2-diphenylethane-1,2-diamine 
• 1296689-77-4 C₂₄H₂₅NO₂ 
• 132836-42-1 1-(α-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline 
• 1394847-03-0 1-(4-methoxyphenyl)-2-phenylphenanthrene 
• 1394847-08-5 2-ethyl-1-phenylphenanthrene 
• 1394847-06-3 1,2-di-p-tolylphenanthrene 

Relevant articles and documents

Palladium-Catalyzed Reductive Conversion of Acyl Fluorides via Ligand-Controlled Decarbonylation

Ligand-controlled non-decarbonylative and decarbonylative conversions of acyl fluorides were developed using a Pd(OAc)2/Et3SiH combination. When tricyclohexylphosphine (PCy3) was used as the ligand, aldehydes were obtained as simple reductive conversion products. The use of 1,2-bis(dicyclohexylphosphino)ethane (Cy2P(CH2)2PCy2, DCPE) as the ligand, however, favored the formation of hydrocarbons, which are decarbonylative reduction products.

Catalytic Asymmetric Epoxidations with Chiral Iron Porphyrins

Iron porphyrins have been modified to include optically active functionalities at the meso positions.Asymmetric epoxidations of prochiral olefins with these chiral iron porphyrins and iodosyl compounds have been investigated.Thus, 5α,10β,15α,20β-tetrakis(o-(R)-hydratropamidophenyl)porphyrin (H2T(α,β,α,β-Hyd)PP) and 5α,10β,15α,20β-tetrakis(ophenyl)porphyrin (H2T(α,β,α,β-Binap)PP) were synthesized by the condensation of optically active acid chlorides with 5α,10β,15α,20β-tetrakis(o-aminophenyl)porphyrin.Subsequent insertion of iron into H2T(α,β,α,β-Hyd)PP and H2T(α,β,α,β-Binap)PP gave FeT(α,β,α,β-Hyd)PPCl and FeT(α,β,α,β-Binap)PPCl, respectively.Emploing FeT(α,β,α,β-Hyd)PPCl iodosylbenzene, styrene was oxidized to (R)-(+)-styrene oxide in 31percent ee.Similarly, FeT(α,β,α,β-Binap)PPCl and iodosylmesitylene gave (R)-(+)-styrene oxide in 48percent ee.Various substituted styrenes and aliphatic olefins were epoxidized with enantiomeric excesses varying between 0percent for 1-methylcyclohexene oxide and 51percent for p-chlorostyrene oxide.