43017-75-0

Usage

Uses

Used in Pharmaceutical Industry:
Naphthalen-1-yl-acetaldehyde is used as an intermediate in the synthesis of pharmaceuticals for its potential biological activity. It contributes to the development of drugs that target various health conditions due to its inherent properties.
Used in Agrochemical Industry:
Naphthalen-1-yl-acetaldehyde is also utilized in the synthesis of agrochemicals, specifically for its potential to exhibit pesticidal properties, thereby aiding in the protection and enhancement of crop yields.
Used in Research and Development:
Naphthalen-1-yl-acetaldehyde serves as a valuable compound in research settings, where it is studied for its antibacterial, antifungal, and anti-inflammatory properties, as well as its potential application in treating neurodegenerative diseases.

Upstream product

• 826-74-4 1-vinylnaphthalene 
• 86-87-3 naphth-1-yl acetic acid 

Downstream Products

• 86-87-3 naphth-1-yl acetic acid 
• 2091-90-9 1,2,3,4-tetrahydrochryzene 
• 874338-50-8 1-(1-naphthyl)-4-phenylbut-3-yn-2-ol 
• 1296689-77-4 C₂₄H₂₅NO₂ 
• 132836-42-1 1-(α-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline 
• 1431696-11-5 (E)-1-(3-(phenylsulfonyl)allyl)naphthalene 
• 1431696-17-1 (E)-1-(3-(phenylsulfonyl)prop-1-en-1-yl)naphthalene 
• 132-75-2 naphthalen-1-ylacetonitrile 
• 66-77-3 1-naphthaldehyde 

Relevant academic research and scientific papers

Palladium-Catalyzed Reductive Conversion of Acyl Fluorides via Ligand-Controlled Decarbonylation

Ligand-controlled non-decarbonylative and decarbonylative conversions of acyl fluorides were developed using a Pd(OAc)2/Et3SiH combination. When tricyclohexylphosphine (PCy3) was used as the ligand, aldehydes were obtained as simple reductive conversion products. The use of 1,2-bis(dicyclohexylphosphino)ethane (Cy2P(CH2)2PCy2, DCPE) as the ligand, however, favored the formation of hydrocarbons, which are decarbonylative reduction products.

Selective switchable iron-catalyzed hydrosilylation of carboxylic acids

Selective reduction of carboxylic acids either to aldehydes or alcohols is achieved using a one pot procedure based on iron-catalyzed hydrosilylations. Using phenylsilane and (COD)Fe(CO)3 catalyst under UV-irradiation at rt, alcohols were obtained specifically in good yields, whereas aldehydes were selectively obtained using TMDS and (t-PBO)Fe(CO)3 catalyst under thermal activation.

Catalytic Asymmetric Epoxidations with Chiral Iron Porphyrins

Iron porphyrins have been modified to include optically active functionalities at the meso positions.Asymmetric epoxidations of prochiral olefins with these chiral iron porphyrins and iodosyl compounds have been investigated.Thus, 5α,10β,15α,20β-tetrakis(o-(R)-hydratropamidophenyl)porphyrin (H2T(α,β,α,β-Hyd)PP) and 5α,10β,15α,20β-tetrakis(ophenyl)porphyrin (H2T(α,β,α,β-Binap)PP) were synthesized by the condensation of optically active acid chlorides with 5α,10β,15α,20β-tetrakis(o-aminophenyl)porphyrin.Subsequent insertion of iron into H2T(α,β,α,β-Hyd)PP and H2T(α,β,α,β-Binap)PP gave FeT(α,β,α,β-Hyd)PPCl and FeT(α,β,α,β-Binap)PPCl, respectively.Emploing FeT(α,β,α,β-Hyd)PPCl iodosylbenzene, styrene was oxidized to (R)-(+)-styrene oxide in 31percent ee.Similarly, FeT(α,β,α,β-Binap)PPCl and iodosylmesitylene gave (R)-(+)-styrene oxide in 48percent ee.Various substituted styrenes and aliphatic olefins were epoxidized with enantiomeric excesses varying between 0percent for 1-methylcyclohexene oxide and 51percent for p-chlorostyrene oxide.