43029-26-1Relevant academic research and scientific papers
Synthesis and biological studies of some new thiadiazolo [2,3-a] 1,2,4-triazin-5-ones
Revanasiddappa,Subrahmanyam,Satyanarayana
experimental part, p. 291 - 292 (2011/12/05)
Treatment of thiocarbohydrazide 2 with pyruvic acid 1 in ethanol affords 4-amino-3-mercapto-6-methyl-1,2,4-triazin-5(4H)-one 3. Cyclization of 3 with various aromatic acids in presence of phosphorus oxychloride yields 2-substituted -6-methyI-4H-1,3,4-thiadiazolo [2,3-c], 1,2,4-triazin-5-ones (4a-j). The structures of the newly synthesized compounds have been established by means of IR, Mass, 1H NMR spectral data. All the new compounds (4a-j) were evaluated for their antibacterial and antifungal activities.
New synthesis of [1,3,4] thiadiazolo [2,3-c][1,2,4] triazinone; transfer of active electron by microwaves
Abdi Oskooie,Heravi,Khosrofar,Faridbod
, p. 2399 - 2402 (2007/10/03)
Reaction of various aromatic aldehydes with 4-amino-6-methyl-1,2,4-triazin-5-one supported on to montmorillonite-K10 in the presence of nitrobenzene under microwaves irradiation, afforded the corresponding [1,3,4] thiadiazole [2,3-c][1,2,4]-triazinones.
Synthesis and biological activity studies of 1,3,4-thiadiazolo[2,3-c]-as-triazines
Kalluraya,Sreenivasa,Banji
, p. 266 - 271 (2007/10/03)
Several new 1,3,4-thiadiazolo[2,3-c]-as-triazines were synthesized by the reaction of 6-substituted-4-amino-3-mercapto-1,3,4-triazon-5(4H)-ones with appropriate aromatic and heterocyclic carboxylic acids in the presence of phosphorus oxichloride. The structures of the newly synthesized compounds were established on the basis of analytical, IR, NMR and mass spectral data. Some selected compounds from this series were subjected to both antimicrobial and pharmacological studies.
