430447-31-7Relevant academic research and scientific papers
Ruthenium-Catalyzed Reductive Amidation without an External Hydrogen Source
Yagafarov, Niyaz Z.,Muratov, Karim M.,Biriukov, Klim,Usanov, Dmitry L.,Chusova, Olga,Perekalin, Dmitry S.,Chusov, Denis
supporting information, p. 557 - 563 (2018/02/09)
A catalytic reaction between aldehydes and primary amides that leads to N-alkylated amides was investigated. The developed protocol employs carbon monoxide as a deoxygenative agent and, therefore, avoids the use of an external hydrogen source. Cyclopentad
Chemoselective calcium-catalysed direct amidation of carboxylic esters
Nguyen, D. Thao,Lenstra, Danny C.,Mecinovi?, Jasmin
, p. 77658 - 77661 (2015/09/28)
Unactivated carboxylic esters and primary amines undergo calcium-catalysed direct amide bond formation in excellent yields under homogeneous conditions in toluene. This green and mild reaction proceeds chemoselectively with esters, whereas related carboxylic acids and amides remain unreactive.
Catalytic acylation of amines with aldehydes or aldoximes
Allen, C. Liana,Davulcu, Simge,Williams, Jonathan M. J.
supporting information; experimental part, p. 5096 - 5099 (2011/02/21)
The simple nickel salt NiCl2?6H2O catalyzes the coupling of aldoximes with amines to give secondary or tertiary amide products. The aldoxime can be prepared in situ from the corresponding aldehyde. The use of 18O-labeled oximes has allowed insight into the mechanism of this reaction.
