43057-68-7Relevant academic research and scientific papers
Synthesis of perimidine and 1,5-benzodiazepine derivatives using tamed Br?nsted acid, BF3-H2O
Prakash, G. K. Surya,Paknia, Farzaneh,Narayan, Arjun,Mathew, Thomas,Olah, George A.
, p. 99 - 105 (2013)
The one pot synthesis of perimidine and 1,5-benzodiazepine derivatives via condensation of aryldiamines with ketones in the presence of BF 3-H2O is described. BF3-H2O plays a dual role, as an efficient non-oxidizing Br?nsted acid catalyst as well as an effective solvent making the reaction more economic and environmentally safer. The reaction is simple, fast and convenient.
A novel eco-friendly on-water protocol for the synthesis of 2,2-disubstituted 2,3-dihydro-1H-perimidines
Harry, Nissy Ann,Shilpa, Thomas,Ujwaldev, Sankuviruthiyil M.,Anilkumar, Gopinathan
, p. 375 - 381 (2020/10/06)
An efficient green on-water protocol for the synthesis of 2,2-disubstituted 2,3-dihydro-1H-perimidines is demonstrated. The reaction used safer p-toluenesulfonic acid (PTSA) as a catalyst on water at 80°C, for 2 hours affording a novel method for the synt
