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2-(4-bromo-phenyl)-3a,4,7,7a-tetrahydro-4,7-methano-isoindole-1,3-dione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

43069-71-2

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43069-71-2 Usage

Molecular Weight

370.22 g/mol

Structure

A tetrahydromethanoisoindole-1,3-dione core with a 4-bromo-phenyl group attached to the 2-position.

Receptor Interaction

A potent and selective inverse agonist of the cannabinoid CB2 receptor.

Potential Applications

In the treatment of various conditions such as inflammatory and neuropathic pain, as well as autoimmune and inflammatory diseases.

Importance

An important compound in the field of medicinal chemistry and drug discovery due to its potential for use in the development of novel therapeutic agents targeting the CB2 receptor.

Check Digit Verification of cas no

The CAS Registry Mumber 43069-71-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,0,6 and 9 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 43069-71:
(7*4)+(6*3)+(5*0)+(4*6)+(3*9)+(2*7)+(1*1)=112
112 % 10 = 2
So 43069-71-2 is a valid CAS Registry Number.

43069-71-2Downstream Products

43069-71-2Relevant academic research and scientific papers

BISREAGENTS IN THE DIELS-ALDER REACTION. VII. PRODUCTION OF POLYADDUCTS FROM THE REACTION OF BISPOLYMETHYLCYCLOPENTADIENES AND BISMALEIMIDES AND THEIR PROPERTIES

Kiselev, V. D.,Sakhabutdinov, A. G.,Shakirov, I. M.,Zverev, V. V.,Konovalov, A. I.

, p. 1806 - 1813 (2007/10/02)

Polymethylcyclopentadienes and bisdienes exhibit high reactivity with mono- and bisdienophiles in the Diels-Alder reaction.By reaction calorimetry in solution, differential scanning calorimetry, and derivatography it was found that the mono-, bis-, and polyadducts have high thermal stability.The ionization potentials, determined for a series of dienes by photoelectron spectroscopy and spectrophotometry of charge-transfer complexes, lie in the range of 7.15-8.5 eV.The coefficients of the Kuhn-Houwink equation were calculated from data on the characteristic viscosity of the solutions of the polyadducts.They agree with the spherical shape of the polyadducts.The molecular mass of the new polyadducts is greater than 100000.

KINETIC AND THERMODYNAMIC STUDY OF THE DIELS-ALDER REACTION WITH 1,2,3,4,5-PENTAMETHYLCYCLOPENTADIENE

Kiselev, V. D.,Sakhabutdinov, A. G.,Shakirov, I. M.,Konovalov, A. I.

, p. 2276 - 2278 (2007/10/02)

A kinetic and thermochemical study of the Diels-Alder reaction between 1,2,3,4,5-pentamethylcyclopentadiene and a series of dienophiles was undertaken.The ionization potential of the diene (7.08 eV) was calculated from the spectrum of the charge-transfer complex with p-chloranil.Pentamethylcyclopentadiene was more reactive than cyclopentadiene, 9,10-dimethylanthracene, and even 2,5-diphenylisobenzofuran.The exothermicity of the reactions of the dienophiles with pentamethylcyclopentadiene in benzene is appreciably higher than in the reactions with other dienes.An important feature of the investigated diene is the favorable combination of its enhanced reactivity in the Diels-Alder reaction with the enhanced stability of its adducts.

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