43071-45-0

Basic information

• Product Name: 3-METHYL-2-PHENYL-QUINOLINE-4-CARBOXYLIC ACID
• Synonyms: AKOS AUF0352;3-METHYL-2-PHENYL-QUINOLINE-4-CARBOXYLIC ACID;CHEMBRDG-BB 3000590;3-methyl-2-phenylquinoline-4-carboxylic acid(SALTDATA: FREE);4-Quinolinecarboxylicacid, 3-Methyl-2-phenyl-;3-methyl-2-phenyl-cinchoninic acid
• CAS NO: 43071-45-0
• Molecular Formula: C₁₇H₁₃NO₂
• Molecular Weight: 263.29
• Mol File: 43071-45-0.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 443.2 °C at 760 mmHg
• Flash Point: 221.8 °C
• Appearance: /
• Density: 1.248 g/cm³
• Vapor Pressure: 1.23E-08mmHg at 25°C
• Storage Temp.: 2-8°C
• PKA: 0.97±0.10(Predicted)
• CAS DataBase Reference: 3-METHYL-2-PHENYL-QUINOLINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-2-PHENYL-QUINOLINE-4-CARBOXYLIC ACID(43071-45-0)
• EPA Substance Registry System: 3-METHYL-2-PHENYL-QUINOLINE-4-CARBOXYLIC ACID(43071-45-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 43071-45-0(Hazardous Substances Data)

Usage

General Description

3-Methyl-2-phenyl-quinoline-4-carboxylic acid is a chemical compound with the molecular formula C18H13NO2. It is a derivative of quinoline, containing a methyl group at the 3-position and a phenyl group at the 2-position. The carboxylic acid group is located at the 4-position of the quinoline ring. 3-METHYL-2-PHENYL-QUINOLINE-4-CARBOXYLIC ACID has potential applications in the pharmaceutical industry, as it may exhibit biological activity that could make it useful as a drug or as a precursor for drug synthesis. Additionally, it may have applications in the field of organic synthesis and materials science due to its unique structure and properties.

InChI:InChI=1/C17H13NO2/c1-11-15(17(19)20)13-9-5-6-10-14(13)18-16(11)12-7-3-2-4-8-12/h2-10H,1H3,(H,19,20)/p-1

Upstream product

• 91-56-5 indole-2,3-dione 
• 93-55-0 1-phenyl-propan-1-one 
• 43071-31-4 3-(carboxymethyl)-2-phenylquinoline-4-carboxylic acid 
• 2051-95-8 succinylbenzene 

Downstream Products

• 174636-71-6 3-methyl-2-phenylquinoline-4-carbonyl chloride 
• 224633-15-2 3-(bromomethyl)-2-phenylquinoline-4-carboxylic cid 
• 181048-13-5 2-phenyl-3-methylquinoline-4-carbonylguanidine 
• 5471-16-9 3-methyl-2-phenylquinoline-4-carboxylic acid ethyl ester 
• 74960-43-3 3-methyl-2-phenyl-quinoline-4-carboxylic acid methyl ester 
• 1071566-96-5 3-methyl-2-phenyl-quinoline-4-carboxylic acid-(2-chloro-ethyl ester) 
• 402517-03-7 3-methyl-2-phenylquinoline-4-carbohydrazide 
• 74960-55-7 methyl 1-acetyl-2-phenylindole-3-carboxylate 
• 65417-21-2 methyl 3-methyl-2-phenylquinoline-4-carboxylate 1-oxide 
• 36779-17-6 methyl 2-phenyl-1H-indole-3-carboxylate 
• 65417-28-9 methyl 3-acetyl-2-phenyl-3H-indole-3-carboxylate 
• 65417-26-7 methyl 4-methyl-2-phenyl-3,1-benzoxazepine-5-carboxylate 

Relevant articles and documents

Synthesis and Antimicrobial Activity of 1,3,4-Oxadiazole-2(3H)-thione and Azidomethanone Derivatives Based on Quinoline-4-carbohydrazide Derivatives

A new series compounds of quinoline derivatives were synthesized by reaction of 3-(carboxymethyl)-2-arylquinoline-4-carboxylic acids 1a, 1b, 1c with different nucleophiles. The structures of the new compounds were elucidated on the basis of FTIR,1/s

Quinoline derivatives as neurokinin receptor antagonists

The present invention relates to substituted quinoline hydrazides of Formula (I): wherein R1, R2, R3, R4, R5, X, Y and Z are defined herein, pharmaceutical compositions comprising them and their use in treating diseases mediated by neurokinin-2 and/or neurokinin-3 (NK-3) receptors. These compounds can thus be used in methods of treatment to suppress and treat such disorders.

QUINOLINE 4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS NEUROKININ 3 (NK-3) RECEPTOR ANTAGONISTS

The invention relates to novel quinoline derivatives, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments particularly in treating disorders of the central nervous system (CNS).