43073-71-8Relevant academic research and scientific papers
Synthesis of chalcones derived from 1-naphthylacetophenone and evaluation of their cytotoxic and apoptotic effects in acute leukemia cell lines
Jacques, Amanda Virtuoso,Stefanes, Natália Marcéli,Walter, Laura Otto,Perondi, Daiane Mari,Efe, Fernanda da Luz,de Souza, Luiz Felipe Schmitz,Sens, Larissa,Syracuse, Stephanie Milis,de Moraes, Ana Carolina Rabello,de Oliveira, Aldo Sena,Martins, Carolina Teixeira,Magalhaes, Luma Godoy,Andricopulo, Adriano Defini,Silva, Lisandra de Oliveira,Nunes, Ricardo José,Santos-Silva, Maria Cláudia
, (2021/09/10)
Chalcones and their derivatives have been described as promising compounds with antiproliferative activity against leukemic cells. This study aimed to investigate the cytotoxic effect of three synthetic chalcones derived from 1-naphthylacetophenone (F07,
Synthesis of 1,3,5-trisubstituted pyrazoline nucleus containing compounds and screening for antimicrobial activity
Agrawal, Manish,Sonar, Pankaj Kumar,Saraf, Shailendra K.
, p. 3376 - 3381 (2013/02/25)
In this study, a novel series of heterocyclic compounds containing pyrazoline nucleus has been synthesized. The compounds were synthesized in two steps. Chalcone was synthesized in the first step by Claisen-Schmidt reaction, using 1-Acetylnaphthalene and
Synthesis and screening of substituted chalcones as lipoxygenase inhibitors
Ahmed, Umair,Kaskhedikar,Ahmad, Zafar,Ahmed, Shahzad
experimental part, p. 4993 - 4996 (2012/07/03)
The present work involved the synthesis of chalcone derivatives, their characterization and in vitro evaluation for lipoxygenase inhibitory activity. The synthesis of chalcone derivatives was carried out in one step employing Claisen Schmidt condensation.
Synthesis, in vitro antibacterial and antifungal evaluations of 2-amino-4-(1-naphthyl)-6-arylpyrimidines
Ingarsal,Saravanan,Amutha,Nagarajan
, p. 517 - 520 (2008/02/09)
A series of 2-amino-4-(1-naphthyl)-6-arylpyrimidines have been synthesized and characterized by IR, NMR, MS, elemental analyses and evaluated for in vitro antibacterial and antifungal activities. Some of the compounds were found to be active against a limited panel of bacteria and fungi. In particular, compounds 4b and 4e were found to be the most effective analogs against the tested bacterial and fungal strains.
