43087-19-0 Usage
Description
PENTANEDIOIC-3,3-D2 ACID, with the CAS number 43087-19-0, is an isotopically labeled research compound that is utilized in various scientific studies and experiments. Its unique isotopic composition allows for the tracking and analysis of chemical reactions and processes, making it a valuable tool in the field of research.
Uses
Used in Research Applications:
PENTANEDIOIC-3,3-D2 ACID is used as an isotopically labeled compound for the purpose of studying chemical reactions and processes. Its isotopic labeling enables researchers to track and analyze the behavior of the compound within complex systems, providing valuable insights into reaction mechanisms and pathways.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, PENTANEDIOIC-3,3-D2 ACID is used as a research tool for the development and optimization of drug candidates. Its isotopic labeling allows for the investigation of drug metabolism, pharmacokinetics, and pharmacodynamics, aiding in the design of more effective and safer medications.
Used in Environmental Studies:
PENTANEDIOIC-3,3-D2 ACID is also utilized in environmental studies to understand the fate and transport of pollutants and contaminants in various ecosystems. Its isotopic labeling helps in tracking the movement and transformation of these substances, contributing to the development of strategies for environmental remediation and protection.
Used in Analytical Chemistry:
In the field of analytical chemistry, PENTANEDIOIC-3,3-D2 ACID serves as an internal standard or a reference compound in various analytical techniques. Its isotopic composition provides a reliable basis for the quantification and identification of target analytes, improving the accuracy and precision of analytical measurements.
Check Digit Verification of cas no
The CAS Registry Mumber 43087-19-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,0,8 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 43087-19:
(7*4)+(6*3)+(5*0)+(4*8)+(3*7)+(2*1)+(1*9)=110
110 % 10 = 0
So 43087-19-0 is a valid CAS Registry Number.
43087-19-0Relevant articles and documents
Identification of a Pyrrole Intermediate Which Undergoes C-Glycosidation and Autoxidation to Yield the Final Product in Showdomycin Biosynthesis
Kim, Minje,Liu, Hung-wen,Ren, Daan,Wang, Shao-An
supporting information, p. 17148 - 17154 (2021/06/28)
Showdomycin is a C-nucleoside bearing an electrophilic maleimide base. Herein, the biosynthetic pathway of showdomycin is presented. The initial stages of the pathway involve non-ribosomal peptide synthetase (NRPS) mediated assembly of a 2-amino-1H-pyrrole-5-carboxylic acid intermediate. This intermediate is prone to air oxidation whereupon it undergoes oxidative decarboxylation to yield an imine of maleimide, which in turn yields the maleimide upon acidification. It is also shown that this pyrrole intermediate serves as the substrate for the C-glycosidase SdmA in the pathway. After coupling with ribose 5-phosphate, the resulting C-nucleoside undergoes a similar sequence of oxidation, decarboxylation and deamination to afford showdomcyin after exposure to air. These results suggest that showdomycin could be an artifact due to aerobic isolation; however, the autoxidation may also serve to convert an otherwise inert product of the biosynthetic pathway to an electrophilic C-nucleotide thereby endowing showdomycin with its observed bioactivities.
Synthesis of some symmetrically deuterated cyclohexanones
Lompa Krzymien,Leitch
, p. 331 - 338 (2007/10/12)
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