43100-26-1

Upstream product

• 120-47-8 Ethyl 4-hydroxybenzoate 
• 99-96-7 4-hydroxy-benzoic acid 
• 5351-23-5 4-hydroxybenzoic acid hydrazide 
• 127-65-1 chloroamine-T 

Downstream Products

• 19532-76-4 N,N'-bis(4-octyloxyphenyl)oxamide 
• 21022-23-1 N,N'-bis-(4-acetoxy-phenyl)-oxalamide 
• 21022-20-8 N,N'-Bis-(4-allyloxy-phenyl)-oxalamide 
• 10600-83-6 2,5-bis-(4-hydroxyphenyl)-1,3,4-oxadiazole 

Relevant academic research and scientific papers

Synthesis of acylhydrazines and, symmetrical and asymmetrical diacylhydrazines from carboxylic acid via the Vilsmeier reagent mediated process

(Chloromethylene)dimethylammonium chloride (Vilsmeier reagent) has been used as an efficient and convenient reagent for the one-pot synthesis of acylhydrazines and symmetrical and asymmetrical diacylhydrazines from carboxylic acids. This reaction proceeded smoothly under mild conditions and it is quite practical, since the starting carboxylic acids can be easily handled and stored. Cleanliness, simplicity of the method and good to excellent yield of products are other advantages of this method.

Epoxy resin bearing diacylhydrazine moiety as a degradable adhesive for traceless oxidative removal

Bisphenols functionalized with diacylhydrazine moieties and ester groups were prepared from 5-hydroxyisophthalic acid by esterification and partial hydrazination, followed by oxidative coupling of the obtained hydrazide. Ester groups with long alkyl chains or polyether increased the solubility of bisphenols in the epoxy resin. The epoxy resin was cured by heating with bisphenols in the presence of a catalytic amount of imidazole, with more rapid curing observed for more soluble bisphenols. The cured resin, with Td5?≈?300?°C, decomposed rapidly when exposed to sodium hypochlorite solution. The above resin could be used as a strong and tough adhesive for metal and glass, whereas it can be easily removed by treatment with sodium hypochlorite solution without any trace. The observed dismantling rate positively correlated with bisphenol solubility.

Microwave-induced conversion of acid hydrazides to N,N′- diacylhydrazines in solvent-free conditions

A new and efficient method of converting acid hydrazides 1 to the corresponding N,N′-diacylhydrazines 2 under microwave irradiation and in solvent-free conditions has been described. Copyright Taylor & Francis Group, LLC.

A simple and efficient oxidation of hydrazides to N,N'-diacylhydrazines using Oxone in an aqueous medium

Substituted aromatic hydrazides have been oxidised to N,N'- diacylhydrazines in high yields using Oxone in an aqueous medium at room temperature.

Oxidation of Hydrazides Using Sodium Perborate: Formation of N,N′-Diacylhydrazines

Substituted aromatic hydrazides react very smoothly with sodium perborate in glacial acetic acid at room temperature to give N,N′-diacylhydrazines in excellent yields and purity.

Oxidation of Aroyl Hydrazines: Part X - Kinetics of Oxidation of Benzoyl Hydrazines by Chloramine-T in Alkaline Medium

The kinetics of oxidation of benzoyl hydrazines by chloramine-T (CAT) in aq. methanol medium in the pH range 8.9-11.5 has been investigated.The order of reaction with respect to the oxidant and substrate is one each.The rate is found to be independent of pH.The reaction is accelerated by electron withdrawing groups and retarded by electron releasing groups, with a ρ value of + 0.80.An increase in the dielectric constant of the medium increases the rate whereas the ionic strength has no significant effect.A suitable mechanism has been suggested.