43134-76-5

Usage

Uses

Used in Pharmaceutical Industry:
4-acetylamino-2-aminobenzoic acid is used as a precursor for the production of various medications, including local anesthetics and anti-inflammatory drugs. Its unique chemical structure allows it to be a key component in the synthesis of these therapeutic agents, contributing to their efficacy and safety.
Used in Textile Industry:
In the textile industry, 4-acetylamino-2-aminobenzoic acid is utilized in the production of dyes and fluorescent brighteners. Its chemical properties enable it to enhance the color and brightness of textiles, improving their aesthetic appeal and performance.
Overall, 4-acetylamino-2-aminobenzoic acid is a multifaceted chemical compound with important applications across different industries, showcasing its versatility and significance in modern chemical synthesis and product development.

InChI:InChI=1/C9H10N2O3/c1-5(12)11-6-2-3-7(9(13)14)8(10)4-6/h2-4H,10H2,1H3,(H,11,12)(H,13,14)

Upstream product

• 21573-29-5 4-acetylamino-2-nitrobenzoic acid 
• 2719-14-4 4-acetylamino-2-nitrotoluene 
• 119-32-4 4-Methyl-3-nitroanilin 
• 606-31-5 2,6-dinitrobenzaldehyde 
• 603-12-3 2,6-dinitrobenzoic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 50-86-2 4-acetamidosalicylic acid 
• 65-49-6 4-Aminosalicylic acid 
• 1606159-07-2 C₁₁H₁₁N₃O₂S 
• 1606159-31-2 C₂₁H₂₂N₄O₃ 

Relevant academic research and scientific papers

Functionalization of quinazolin-4-ones part 1: Synthesis of novel 7-substituted-2-thioxo quinazolin-4-ones from 4-substituted-2-aminobenzoic acids and PPh3(SCN)2

4-(Nitro, amino, acetylamino)-2-aminobenzoic acid were allowed to react with PPh3(SCN)2 and gave the crossholding 7-nitro, 7-acetylamino- and 7-amino-2-thioxo quinazolin-4-ones respectively. The nature of the substituent at position 4 of the 2-aminobenzoic acids has significant influence on the outcome of the cyclisation reaction with PPh 3(SCN)2. Similarly, the nature of the substituent at position 7 of the 2-substituted quinazolin-4-ones significantly affected the ease with which alkylation reactions could be performed. The alkylation selectivity of the 7- substiuted-2-thioxo quinazolin-4-ones was found to depend on the nature of the alkyl halide and the nature of the substituent at position 2.

Phthalocyanine reactive dyestuffs

Phthalocyanine reactive dyestuffs which, in the form of the free acid, have the formula (1) STR1 in which the variable radicals have the meaning given in the description, are prepared by condensation of the corresponding amines with cyanuric fluoride or cyanuric chloride in any desired order. The reactive dyestuffs according to the invention exhibit good wet and light fastness properties and are used for the dyeing and printing of cotton.

Preparation of Some Acetylated, Reduced and Oxidized Derivatives of 2,4-Diaminotoluene and 2,6-Dinitrotoluene

4-Acetylamino-2-hydroxylaminotoluene (4AA2HAT) and 2-hydroxylamino-6-nitrotoluene (2HA6NT) were prepared from 4-acetylamino-2-nitrotoluene (4AA2NT) and 2,6-dinitrotoluene (2,6-DNT), respectively, by reduction with zinc dust and NH4Cl. 2,6-Dinitrobenzylalcohol (2,6-DNB) and 2,6-dinitrobenzoic acid (2,6-DNBA) were prepared from 2,6-dinitrobenzaldehyde (2,6-DNBAl) by reduction with NaBH4 and by oxidation with KMnO4, respectively. 2-Acetylamino-4-aminobenzoic acid (2AA4ABA) was prepared from 4-nitroanthranilic acid (4NAA) by acetylation followed by reduction with NaBH4 and Pd-C. 2,4-Diacetylaminobenzoic acid (2,4-DAABA) was prepared from 4NAA by reduction with NaBH4 and Pd-C followed by acetylation. 4-Acetylamino-2-aminobenzoic acid (4AA2ABA) was prepared from 4NAA by reduction and acetylation followed by chelation with Cu(AcO)2.Keywords- 4-acetylamino-2-hydroxylaminotoluene; 2-hydroxylamino-6-nitrotoluene; 2,6-dinitrobenzylalcohol; 2,6-dinitrobenzoic acid; 2-acetylamino-4-aminobenzoic acid; 4-acetylamino-2-aminobenzoic acid; 2,4-diacetylaminobenzoic acid; carcinogenicity; mutagenicity; preparation