4315-71-3

Usage

Structure

A derivative of triazine and carboxylic acid with a phenyl group attached

Chemical properties

Interesting chemical properties that make it potentially useful in various applications

Pharmaceuticals

Due to its unique structure and properties, it may have potential uses in the development of new drugs

Agrochemicals

It could be used in the development of new pesticides or other agricultural chemicals

Materials science

Its unique structure and properties may make it useful in the development of new materials

Biological activities

It may have biological activities, which could be explored for potential therapeutic or other applications

Building block

It could be used as a building block in the synthesis of various organic compounds

Further research

More research and exploration of its potential uses and properties are needed to fully understand its capabilities and potential benefits

Upstream product

• 65172-73-8 5,7-dimethyl-2-phenyl-2H,5H-pyrimido[4,5-e][1,2,4]triazine-3,6,8-trione 
• 122707-25-9 6-amino-1,3-dimethyl-5-phenylazouracilate 
• 30615-95-3 (2-cyano-2-(2-phenylhydrazino)acetyl)carbamic acid ethyl ester 
• 20932-00-7 2-phenyl-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile 

Downstream Products

• 16280-53-8 2-phenyl-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonyl chloride 
• 76789-41-8 1-phenyl-3-methyl-6-azauracil 
• 4315-66-6 1-phenyl-6-azauracil 

Relevant academic research and scientific papers

General synthesis of 1-Aryl-6-azaisocytosines and their utilization for the preparation of related condensed 1,2,4-Triazines

A simple general synthesis of 1-aryl-6-azaisocytosine-5-carbonitriles 4 is described. This method is based on coupling diazonium salts with cyanoacetylcyanamide 2 and then cyclization of the formed 2-arylhydrazono-2-cyanoacetylcyanamides 3. The 6-azaisocytosines 4 were studied with respect to tautomeric equilibrium and the transformation of functional groups, and used in the synthesis of the condensed heterocyclic compounds: Purine isosteric imidazo[2,1-c]-[1,2,4]triazine 8 and the 1,2,4-triazino[2,3-a]quinazolines 9-12.

QUINOLINE COMPOUND COMPOSING 1,2,4-TRIAZINE-DIONE AND USE THEREOF

The present invention relates to a quinoline deravative represented by general formula (I) or a pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof, wherein Ar, R1, R2, R3, X, Y and n have the meanings given in the description. The present invention also relates to the comparatively strong effect of the compound represented by general formula (I) on inhibiting c-Met kinase. The present invention further relates to the use of this compound or a pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof in the manufacturing of a medicament for treating the disease caused by abnormally over-expressing c-Met kinase, in particular, for treating or preventing cancer.