431888-57-2

Basic information

• Product Name: 2-Chloro-4-(Methoxycarbonyl)benzoic acid
• Synonyms: 2-Chloro-4-(Methoxycarbonyl)benzoic acid;2-Chloro-4-(methoxycarbonyl)
• CAS NO: 431888-57-2
• Molecular Formula: C₉H₇ClO₄
• Molecular Weight: 214.60248
• Mol File: 431888-57-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 360.3±27.0 °C(Predicted)
• Appearance: /
• Density: 1.413±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.43±0.25(Predicted)
• CAS DataBase Reference: 2-Chloro-4-(Methoxycarbonyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-(Methoxycarbonyl)benzoic acid(431888-57-2)
• EPA Substance Registry System: 2-Chloro-4-(Methoxycarbonyl)benzoic acid(431888-57-2)

Safety Data

• Hazardous Substances Data: 431888-57-2(Hazardous Substances Data)

Usage

General Description

2-Chloro-4-(Methoxycarbonyl)benzoic acid is a chemical compound that belongs to the class of benzoic acids, specifically containing a chlorine atom at the 2 position and a methoxycarbonyl group at the 4 position on the benzene ring. It is a white powder with a molecular formula of C9H7ClO4 and a molecular weight of 212.6 g/mol. 2-Chloro-4-(Methoxycarbonyl)benzoic acid is used in the synthesis of various pharmaceuticals and agrochemicals, and it also has potential applications in organic synthesis and medicinal chemistry. It is important to handle this chemical with caution as it may pose health hazards if not properly managed.

Upstream product

• 18643-84-0 2-chloro-1,4-benzenedicarboxylic acid dimethyl ester 

Downstream Products

• 55737-63-8 3-Chloro-4-chlorocarbonyl-benzoic acid methyl ester 
• 879087-10-2 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonylmethyl)benzamide 
• 1190947-57-9 2-chloro-4-(methylsulfonylmethyl)benzoic acid 
• 1190947-56-8 tert-butyl 2-chloro-4-(methylsulfonylmethyl)benzoate 
• 879088-82-1 tert-butyl 4-(bromomethyl)-2-chlorobenzoate 
• 1190947-53-5 tert-butyl 2-chloro-4-(hydroxymethyl)benzoate 
• 431888-58-3 1-tert-butyl 4-methyl 2-chloroterephthalate 

Relevant articles and documents

BICYCLOHETEROARYL-HETEROARYL-BENZOIC ACID COMPOUNDS AS RETINOIC ACID RECEPTOR BETA (RARβ) AGONISTS

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain bicycloheteroaryl-heteroaryl-benzoic acid compounds of the following formula (for convenience, collectively referred to herein as "BHBA compou

PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING

The invention provides novel inhibitors of hedgehog signaling that are useful as s therapeutic agent for treating malignancies where the compounds have the general formula (I): where A, X, Y R1, R2, R3, R4, m and n are as described herein.

Process and intermediates for the preparation of halogenated protease inhibitors

This invention relates to novel intermediate compounds which are useful for producing the halogenated protease inhibitors that are the subject matter of U.S. Pat. No. 4,469,885. In particular, the invention relates to novel methods and intermediates for making said protease inhibitors, the intermediate compounds being of the formula: STR1 wherein R1 is: (a) straight or branched chain lower alkyl having 1-6 carbon atoms; or (b) H; wherein R6 is: (a) straight or branched chain higher alkyl having 13-25 carbon atoms; or (b) straight or branched chain higher alkenyl having 13-25 carbon atoms; wherein R5 is: (a) straight or branched chain lower alkyl having 1-6 carbon atoms; or (b) benzyl; wherein R7 is: (a) straight or branched chain lower alkyl having 1-6 carbon atoms; or (b) H; wherein R2 is: (a) --Cl, --Br, or --I; or (b) --CF3.